POISONED ARROWS OF THE ABORS AND MISHMIS OF NORTH-EAST INDIA. 921 



T a b lb XI X — continued. 



Date. 



Weight 



of 

 Animal. 



Dose 

 per 



Kilo. 



Actual 

 Uose. 



Result. 



Notes. 



1914. 

 May 11 



June 8 

 „ 8 



22 



30 

 30 



002 



0-025 

 05 



0-00044 



0-00075 

 0-00115 



Death in less 

 than 18 hours. 



Death in from 

 4 to 5 days. 



Death in about 

 2 days. 



Injection made in ventral aspect of leg. In this 

 experiment, also, no symptom was observed 

 during life. After death, much blood was 

 extravasated into the alimentary canal and 

 was more equally distributed in the stomach 

 and small and large intestines. There was no 

 congestion or haemorrhage in any part of the 

 posterior extremities or in the subcutaneous 

 or deep tissues anywhere, and they, as well 

 as the brain and spinal cord, appeared rather 

 pale (Plate C, fig. 1). 



No change in rate of cardiac or respiratory 

 movements. On 2nd day, motor weakness. 

 On 2nd and 4th days, blood-stained gelatin- 

 ous matter passed per ano. After death, 

 heart motionless, but when touched the ven- 

 tricle contracted regularly 42 per minute for 

 5 minutes, then slowed and soon stopped in 

 diastole. Haemorrhages in tissues of injected 

 leg, thigh, and foot. Much blood in the 

 stomach and intestines. 



Do. do. After death, in leg injected purplish- 

 red discoloration of the gastrocnemius, and 

 punctiform haemorrhages in all the muscles 

 of the leg and foot and a minute haemorrhage 

 in the right and left pectoral muscles. Dark 

 fluid blood in heart ami larger blood-vessels. 

 Blood-stained fluid in peritoneum. Stomach 

 and intestines contain blood. 



In the second of these series, particular attention may be drawn to the experi- 

 ments with O'Ol and 0*02 grm. per kilo. In both of them, large lethal doses of ether 

 extract were injected under the skin of the ventral aspect of a leg below the knee, 

 and quickly produced death ; but in the examination made after death, while there 

 was no haemorrhage or even congestion in the part where the poison had been 

 injected, nor even in any part of the injected limb or other subcutaneous or deep 

 tissue of the body, still a large quantity of blood was found in the alimentary canal. 

 In the experiment in which the smaller dose (0'01 grm. per kilo) had been injected, 

 nearly all of this blood was found in the stomach; but it was more equally dis- 

 tributed throughout the alimentary canal — in the stomach, small intestine, and large 

 intestine — in the experiment in which the larger dose (0"02 grm. per kilo) had been 

 injected. The results of the latter experiment are well depicted in the drawing 

 (Plate C, fig. l), which also shows the absence of haemorrhage or even congestion 

 at the ventral aspect of the left leg where the poison had been introduced. 



TRANS. ROY. SOC. ED1N., VOL. L, PART IV (NO. 28). 



131 



