MULTIPLE NEUROMATA OF THE CENTRAL NERVOUS SYSTEM. Tb 
the retained glia framework, may for a time conform to the plan of the normal strands 
of the part involved, but, in their further evolution, they became tortuous and inter- 
twined and convoluted, and form the nodules described in (4). The simplest patches 
described in (1) (@), we regard as sections of the margins of a patch of nucleated strands 
similar to those in (3). The nodules described in (5); in relation to the superficial 
origin of the motor nerves, we also take to owe their origin to the proliferation of 
spindle-shaped cells, which form nucleated tubes and nodules. The nodules have then 
undergone a fibrosis, which involves the emerging roots. The small areas of fibrosis in 
(6) are areas of a fibrous transformation affecting blood-vessels, nucleated tubes, and 
spindle-shaped cells. 
Finally, the nucleated patches described in (1) (b), cut transversely and longitudinally, 
we relate to transverse and longitudinal strands of sensory nerves in their path to their 
nuclei of origin. An explanation of the areas described in (2) in relation to the sensory 
nerves is extremely diflicult. A comparison of their extra-medullary and intra-medullary 
course shows that within the brain the interstitial tissue and nucleation is more evident, 
and the impression is confirmed that here also not only had the neurilemma sheath been 
carried inwards, but pial fibrous tissue also, and that within the brain this connective 
_ tissue element in relation to the fibres had increased. The change must be related to, 
and have the same explanation as, the fibrosis affecting the posterior roots of the cord ; 
but further than this it is impossible to go. 
To complete this histological study it is necessary to refer briefly to the presence of 
several abnormalities which can here be grouped together. 
At the level of the point of emergence of the 7th nerve, a curious condition is to 
iCR- 
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V Nerve 
hf Roof: ~~ - ° 
oat 
vi Nerve ~ : . = ae Ya 
vii Nuel i VI | 
\punwads 
Py r Fibres. 
Fic. F, 
TRANS. ROY. SOC. EDIN., VOL. XLVIII. PART III. (NO. 27). : 111 
