798 MULTIPLE NEUROMATA OF THE CENTRAL NERVOUS SYSTEM. 
Figs. 44-46, Paraffin sections from 3rd sacral segment, Van Gieson’s stain, showing nodule in region of 
central canal (fig. 44, x 160), and in successive serial sections the unravelling of the nodule into nucleated 
fibres (fig. 45, x 160), and a meshwork of individualised nucleated elements (fig. 46, x 160). 
Pirate VI. 
Fig. 47. Posterior root-entry zone (3rd lumbar segment), to show the Ablasswngzone, or constriction zone, 
or ring of Obersteiner. Kulschitzky-Pal. x 50. : 
Fig. 48, Anterior root-emergent zone (7th cervical segment), to show similar Ablassungzone in relation to 
the anterior roots. Kulschitzky-Pal. x 70. 
Fig. 49. Glia cell proliferation and hyperplasia. Cf. fig. 7. Van Gieson’s stain. x 180. 
Fig. 50. Anterior horn cells, showing only slight changes. Note well-marked vacuolation in a cell at 
lower border of figure. Unna’s polychrome methylene blue stain. x 100. 
Fig. 51. Transverse section of cord at level of 2nd lumbar segment: areas of marked fibrosis, often 
almost symmetrical in the anterior horns. Kulschitzky-Pal and picro-fuchsin. x 10. 
Fig. 52. Dense area of fibrosis at base of anterior horn, and stretching amongst the antero-mesial and 
postero-lateral groups of cells. Kulschitzky-Pal and picro-fuchsin. x 20. 
Fig, 53. Fibrosis of posterior root. Extra-medullary root gives the impression of having been carried 
right into the cord substance with its extra-medullary structure. Van Gieson’s stain. x 35. : 
Fig. 54. Fibrosis of intramedullary course of anterior root. The neurilemma, together with a layer of 
the pia, seems as if carried inwards along individual bundles of fibres. Van Gieson’s stain. x 160. 
Fig. 55, Granular deposit, often coalescing to form concretions, found in the adventitial spaces of the 
smaller vessels of the tissue, in close relation to the malformation described on page 778. Van Gieson’s 
stain. x 250. 
Fig. 56. Fibrosis of intra-medullary course of 5th nerve. Cf. fig. 53. Van Gieson’s stain. x 24. 
Fig. 57. Isolated nucleated patch (cut longitudinally) on the course of deep strands of 5th nerve. The 
affected fibres retain the normal arrangement of the fibre strands of the part involved. Van Gieson’s stain. 
x 60. 
Fig. 58. Isolated nucleated patch, similar to above, but cut transversely. Van Gieson’s stain. x 60. 
Puares VII. anv VIII. 
Figs, 59-66. Paraffin sections from medulla oblongata. Cf. figs. 1-5 and fig. 14. 
Figs. 59 and 60. Loose meshwork of interlacing nucleated fibres and elongated nucleated elements. 
Fusiform cells (cf. fig. 1) are seen linked together, by their processes, to form cell chains, and by the fusion 
of the imbricated ends there is a transition into nucleated plasmodial bands or “tubes” (cf. fig. 2). Note 
appearances as of dichotomous division, and that the nucleus lies definitely within the cell outline or within 
the “lumen” of the “tube.” Fig. 59 ( x 200), fig. 60 (x 400). Van Gieson’s stain. 
Figs. 61 and 62. Convergence of nucleated ‘‘tubes” to form more or less parallel bundles or strands, 
between which similar elements are found cut transversely. Presence of small amount of interfibrillar 
connective tissue and delicate capillaries. Fig. 61 ( x 160), fig. 62 (x 160.) Van Gieson’s stain. 
Fig. 63. Commeucing intertwining of the parallel strands. Such intertwining forms the transition to 
the definite nodule in fig. 64. Van Gieson’s stain. x 200. 
Fig. 64. Nodule on floor of 4th ventricle, situated laterally and posteriorly to the strands of the 7th 
nerve—a further stage of the intertwining in fig. 63. Wan Gieson’s stain. x 25. 
Figs. 65 and 66. Commencing myelination of the nucleated “tubes.” Note the lattice-work appearance 
of the newly-formed myelin. Heidenhain’s iron-hematoxylin stain. Fig. 65 (x 450), cf. fig. 14, a, b, ¢. 
Fig. 66 (x 450), ef. fig. 14, d, e, f. 
PRESS 2TED 
235 JUL. 1918 
