328 General Notes. (March, 
periphery with a thin continuous layer of modified protoplasm; 
the framework in some cases has the form of a network of smal 
threads of equal size as described by Klein, in others of flattened 
bands. Further, the threads or bands may vary in size indi 
ferent parts of the cell, and the meshes in different parts of the 
cell may be of different size and shape. Within the meshes of 
the framework are enclosed two chemical substances at leat 
viz., (6) a hyaline substance in contact with the framework, a 
of (c) spherical granules which are embedded in the hyaline st 
stance. In the gland cells which secrete much organic mati 
the cell granules are conspicuous and fairly large. In the gland 
cells which secrete comparatively little organic matter the cel 
granules are, generally speaking, smaller and Jess distinct, t 
lower the mean percentage of organic matter is in the fuid 
secreted. The cell-granules are in nearly all cases mesostales, 
î. e., substances stored up in the cell and destined to give pee 
the organic substances of the secretion. The granularity ofa : 
in the resting state thus depends upon its storage power. OP" 
ally speaking, the greater the storage power of a cell, the high 
is the percentage of the organic substance in its secretions, ™ 
this is not always the case, since it may happen that the < 
secretion of water may increase without any corresponding i 
crease in the rate of secretion of organic substance, and e may 
quence the percentage of organic substance in the secretio ie 
be small; further, it is possible that under special circums" i 
Hath ight secrete a large q 
a cell with small storage power mig large storage 
"A 
changes take place: The granules decrease in number, 
usually, if not always, in size; the hyaline substance 
in amount; the network grows. The i Bacar 
work is much less than that of the bya 
Moreover, in the majority of cells the details © 
which take place are much the same. The hyaline ie 
creases chiefly in the outer region of the cells, 
disappear from this region, so that an outer non- 
and aninner granular zone are formed. its mes 
throughout the cell in all cases. In the outer zone pag 
filled with hyaline substance; in the inner 200 xe 
filled with granules and a smal] amount of hya fe | 
he glands in which an outer non-granular PR A the frog” 
toad, the gastric glands of ihe snake, and t pr 
pa r i to be remembered that ther iy being : 
