112 THE BOTANICAL MAGAZINE. [Vol xxr. No. 29v. 



and slight paralysis of the sensory nerve set in the pain was 

 intense. The patients knew that the pain could be lessened 

 by cooling the affected parts, but. immediately after the pain 

 became more violent. The pulse beat was weak (about 80 in 

 a minute). There was not detected any change in respiration 

 and temperature, nor any sign of nausea or action of diminished 

 appetite. No impediment in motor nerve was visible but a 

 sensory nerve was slightly affected. 



Case 4.^This is the case examined by Saito in Kyoto in 

 1887. 



1st patient anonym (man) . . 67 in age. 



2nd patient anonym (wife of 1st patient) .... 60 in age. 



3rd patient anonym (son of 1st patient) 19 in age. 



4th patient anonym (son of 1st patient) 13 in age. 



(a family of peasants living in Yamashina-mura Ujigori, Kyoto 

 prefecture.) 



These four persons having collected some ^'Sasatake," grow- 

 ing in a neighboring bamboo woods, cooked them with c^gg 

 plant in Shoyu-soup, and partook of them in the evening. 

 The next morning all began to feel severe pains in the distal 

 portion of the limbs, from the fingers to the elbows in the arms 

 and from the toes to the knees in the legs. The^^ had no 

 pain in the viscera nor w^ere there an}^ symptoms of vomiting 

 or diarrhoea. The pain in the limbs appeared to be diminished 

 by dipping them into cool water, but there were no indications 

 that the patients were being cured. So they went to a hos- 

 pital called Kyoto-Ryo-Byoin. The sufferings of patients were 

 slight so that he could endure the pain without cooling the 

 limbs. The condition of the fourth w^as a more severe while 

 that of the first and the second patients was the worst. 



Such was the difference in the degree of the disease among 

 the four patients, but the symptoms were quite similar in 

 each case. The affected part showed swelling, inflammation 

 and burning, which spread towards the elbows in the arms and 

 over the knees in the legs. In the severest case the epidermis 

 of the affected parts peeled off. There were, how^ever, no traces 

 of insomnia, headache, increase of pulsation, asymmetric change 



