AMERICAN FOULBROOD. 



33 



U. S. P.; formic acid, C. P.; salicylic acid, U. S. P.; salol (phenyl 

 salicylate, U. S. P.); and quinin (bisulphate of quinin, U. S. P.). 



In making the inoculations a suspension of scale material in water 

 is added to medicated honey and colonies free from the disease are 

 fed. The different drugs are used in different proportions. Honey, 

 rather than sirup, is employed since the bees will take the drugs in 

 higher proportions when in honey than when in sirup. The strength 

 that they will take varies somewhat with the conditions present. 

 The higher proportions recorded in Table XI summarizing the 

 experiments approximate the maximum amount that can be em- 

 ployed: 



Table XI. — Indicating the effect of drugs on American foulb rood 



Date of 

 experi- 

 ment. 



Drugs. 



Strength. 



Results of inoculation. 



1916. 

 July 11 

 May 29 





1:2000 

 1:1000 

 2:1000 

 1:2000 

 1:1000 

 2:1000 



10:1000 

 4:1000 

 3:1000 

 1:2000 

 1:1000 

 2:1000 

 1:2000 

 1:1000 

 2:1000 

 2:1000 

 3:1000 



10:1000 

 1 





do 





do 





July 11 

 June 20 







do 





Do.. 



do 





May 29 

 Do.. 



do 





Oil of eucalyptus 





July 11 

 Do.. 



Formalin 





Salicylic acid 



[American foulbrood produced. 



May 29 



do 





June 5 



do 





July 11 



Salol 





May 29 



do 





June 5 



do 





July 11 







May 29 



do 





June 5 



do 





From Table XI it will be seen that American foulbrood was pro- 

 duced in all cases in which colonies were fed a suspension of diseased 

 material in honey medicated with betanaphthol, carbolic acid, 

 eucalyptus, formic acid, salicylic acid, salol, and quinin respectively 

 in the proportions noted. In some of the experiments medicated 

 sirup free from the spores was fed to the inoculated colony on a few 

 successive days following the inoculation, and in some instances 

 both preceding and following it. Whether these treatments with 

 the medicated sirup produced any effect on the infection — positive 

 or negative — was not determined definitely. 



The results thus far obtained indicate that the drugs cited here 

 can not be defended upon, for the present at least, in the treatment 

 of American foulbrood. They do not preclude the possibility, 

 however, that other drugs might be used with profit, but they do 

 emphasize the fact that beekeepers should make sure that the value 

 of a drug has been clearly demonstrated before it is used. 



132862°— 19— Bull. 809 3 



