22, BULLETIN 405, U. S. DEPARTMENT OF AGRICULTURE. 
her feet and then tried to walk, but was unable to stand, and lay down 
again. At 10.47 a.m. she was unable to get her breath and went into 
a spasm, in which her legs straightened out very much as though she 
had been poisoned by strychnin. At 10.484 a. m. she was breathing 
again more naturally. She lay upon her side, trembling violently, 
with her hind legs extended rigidly. At 10.50 a. m. she was quiet 
again. At this time she appeared to be a little bloated. At 10.52 
a. m. the muscles were rigidly contracted again, and the trembling 
became more violent; this was followed by a spasm, in which she had 
great difficulty in getting her breath. At 10.55 a. m. she quieted 
down again, and her respiration became more regular and deep. At 
10.56 a. m. another spasm came on. At 10.58 a. m. she was quiet 
again, with pulse 174, strong, and regular. At11a.m. another spasm 
came on, but the animal soon became quiet. At 11.08 a. m. the head 
was thrown back, the heart fluttered, respiration stopped, and at 
11.10 a. m. the animal was dead. For several minutes before death 
the heart action was weak, and just before death she was unable to 
get her breath. The muscles gradually relaxed, the head was drawn 
back, and the heart stopped. 
An autopsy was made upon the animal immediately, but very little — | 
abnormal was found. The heart stopped in systole, and the brain 
and spinal cord were congested. Other than this the animal appeared 
to be normal. 
TYPICAL CASE OF SHEEP NO. 201. 
Sheep No. 201, a ewe weighing 71 pounds, was brought into the 
corrals for feeding on August 16, 1913. On August 17, at 9 a. m., she 
was given 100 grams of ripe dry lupine seeds of Lupinus leucopsis, the — 
seed having been ground in a coffee mill and mixed with 100 grams ~ 
of bran. At 9.30 a. m. this material had been eaten, and she was — 
given 100 grams more of the ground lupine seed, mixed with bran as 
before. At 12.20 p. m. most of this material had been eaten. Her 
respiration was loud and deep, as in a sleeping animal. It was esti- © 
mated that the animal had eaten altogether 175 grams of lupine seed, 
which would be the equivalent of 0.542 pound per 100 pounds of 
animal. 
On August 18, at 7 a. m., the animal appeared drowsy and sleepy. 
At 7.15 a. m. she walked about a lttle, throwing the forelegs out 
and dropping them as though lacking control. She staggered a 
little as she walked and appeared more sleepy than an hour earlier. 
There were some contractions of the surface muscles of the body. — 
Plate IT, figure 1, shows the condition of the animal at this time. At 
8.15 a. m. she was still upon her feet and able to walk around, but 
walked as though tipsy. When standing she appeared sleepy, the 
ears drooped, and the eyes were half closed. She stood with her legs 
bent at the knees and hocks. At 9.12 a. m. she still stood with the 
2 ALT 
Po ee 
