VENOM OF THE AUSTRALIAN BLACK SNAKE. 155 
July 16, 11 a.m.—Has vomited ; tucked up appearance. 
” 2 p.m.—Has passed loose stools but no blood ; lethargic, 
weak on legs. Temperature 38°6° C. 
” 4p.m.—Cannot walk. Breathing laboured and noisy 
(laryngeal). Temperature 38°5° ©. 
” 6 p.m.—Cannot stand. Breathing slow and laboured. 
Has passed a small quantity of urine contain- 
ing no albumen or blood; pupils dilated. 
Temperature 38°3° C. 
Next day, 9a.m.—Found dead. P.M.—Slight extravasation at 
seat of inoculation. Blood partially clotted 
in heart, fluid elsewhere. Examination of 
blood showed no destruction of corpuscles. 
A little urine in bladder, noé albuminous. 
No hemorrhages in any of the organs. 
Kidneys congested but otherwise normal. 
All these experiments are characterised by the absence of the 
usual destructive effects on corpuscles, and kidney complications, 
which I have always noticed with the entire venom when dogs 
have been the animals experimented with. They agree however, 
absolutely with other experiments in which venom previously 
heated to 85° ©. was injected. 
Experiment 6—The same dog which was injected with filtered 
venom ten days previously but recovered. During the interval 
he had been in good health and gained weight. Present weight 
4°25 kilogrammes. 
July 24, 9 a.m.—0-018 gramme of the entire venom injected under 
skin of back. Rectal temperature 39° C. 
» 11:10 a.m.—Has vomited. Nearly dead; heart beats very 
slow and irregular (twenty-four per minute). 
Pupils dilated ; corneal reflex just present. 
Respiration occasional. 
» 11°15 a.m.—Dead. P.M. examination made directly —Small 
fibrinous clot in right ventricle. Vena cava 
contained fluid blood, which clotted instantly 
