LOSS OF NICOTINE FROM NICOTINE DUSTS 5 
TABLE 4.—WNicotine in nicotine sulphate-calcium hydroxide dust 
Strength 1 Strength 2 Strength 3 
eb is f C P Paraf: Cc P Paraf. 
analysis Paste-| Paraf- an- aste-| Paraf- an- aste-] Paraf- Can- 
board | fined aes vas || board | fined os vas || board } fined CE vas 
box | box | bag || box | box | / bag || box | box | J bag 
1922 Per ct. | Per ct. | Per ct. | Per ct. || Per ct. | Per ct. | Per ct. | Per ct. || Per ct. | Per ct.| Per ct. | Per ct. 
Apres 1225 ose ali (404 7. 04 7. 04 7.04 5. 04 5. 04 5. 04 5. 04 2. 41 2. 41 2.41 2. 41 
Nay; bes =|) 6,08, toad [iv 22 | 6.50 4.95] 5.32] 5.24] 486 2.34] 2.36] 2.52 1. 88 
Jue 12) F228 6.24] 6.92] 7.24] 6.00]} 4.40; 4.82] 5.18] 4.56 2.09} 2.11] 2.48 1. 91 
Sept. 12¢-<.2_-| 5.08.) 6.03.| .7.07_} 3.06 3.401) 4. 1 aeeo Oeil, 2490 1.54] 181] 2.50 1,14 
1923 
ebro S09) leoee cee 6.75 | 2.76 2.43 | 3.80] 5.42] 1.73 Aas i daoo ie 245 81 
Detel2-=2s2e25 1.78 | 3.26] 6.40) 1.81 137-1) 2:60) 4.938 | 1.06 |. -.81 }.1.00 | 1.99 67 
TABLE 5.—WNicotine in nicotine sulphate-calcium carbonate dust 
Strength 1 Strength 2 Strength 3 
sae _ Paste-| Paraf. C Paste-| Paraf. C Paste-| Paraf C 
analysis aste-| Paraf- . an- || Paste-| Paraf- an- ||} Paste-| Paraf- an- 
board | fined | 41985] “Vas || board | fined | WS} vas |} board| fined | S985] vas 
box | box | J bag || box | box | / bag || box | box | ! bag 
1922 Per ct.| Per ct. | Per ct.| Per ct. || Per ct.| Per ct.| Per ct.| Per ct. || Per ct.| Per ct.| Per ct. | Per ct. 
ADE Oho ce COPPA BPO | By AVP EW BOF 4.99 |} 4.99] 4.99 | 4.99 IBS a8 3? 2. 33 2. 33 
June 8 222... 5. 86 6. 36 6. 53 4, 02 3. 46 4. 06 4, 56 3. 22 1.31 1. 61 1.98 1. 08 
Sept. 10-24 -22- 4.32 | 5.54 | 6:31 2. 45 2.22) oS. 257 442671 2 42 -82| 1.01 1. 56 60 
1923 
heb: sss Fost | oly] Rapes 6.49 | 1.90 1.90] 3.19 | 4.64] 1.29 -97 |} 1.16} 1.79 96 
INOVO- ee 1 es 25} 6. 27 1. 02 1.16 1.66} 4.08 75 .70 Sitt 1.63 52 
TABLE 6.—Nicotine in nicotine sulphate-plaster of Paris dust 
Strength 1 Strength 2 Strength 3 
aoe oe Paste-| Paraf: Cc Paste-| Paraf. C Paste-| Paraf. Cc 
analysis aste-| Paraf- an- || Paste-| Paraf- an- || Paste-| Paraf- an- 
board | fined Gass vas || board] fined Ces vas || board| fined Ges vas 
box | box | J bag || box | box | / bag || box | box | J bag 
1922 Per ct. | Per ct. | Per ct.' Per ct. || Per ct.| Per ct.| Per ct.| Per ct. || Per ct. | Per ct.| Per ct.| Per ct 
FADE, 16822 5.5 + 6. 70 6. 70 6. 70 6. 70 4. 65 4. 65 4, 65 4. 65 2. 02 2. 02 2. 02 2. 02 
May 1682.2 2 6. 12 6. 50 6. 31 5. 98 4,22 4. 28) (hers. 4. 08 1. 66 1.82 1. 82 1. 55 
gune 16 -2-= =. 5. 88 6. 09 6. 40 5. 03 3. 70 4. 08 4. 38-|b o> 22 1. 56 1.85 98 
Sept. 16__...__ 5.18 | 5.56] 6.78] 4.88 2. 84 3.05 | 4.57 25 51 69 1. 23 1.81 59 
1923 
Hens-16.22. = 3.77 | 5.88 | 6.49] 4.08 2.17 3.08 | 4.41 2.12 . 63 76} 1.67 42 
INGW.162 <2 "2 ary eee 6.30 | 3.78 2.24) 2.31) 4.11 1,99 | 49 a0: |) 2.30 39 
Both calcium hydroxide and calcium carbonate react with nicotine 
sulphate, freeing the alkaloid, which is volatile. Analysis of the 
plaster of Paris showed that it was alkaline enough (equivalent to 
15 per cent calcium carbonate) to react with the nicotine sulphate 
in the weaker dusts, but not alkaline enough to react completely 
with the nicotine sulphate in the stronger dusts. For this reason, 
dusts of this material in different strengths do not behave alike. 
The strongest, containing originally 6.7 per cent nicotine, lost, from 
the canvas bag, 44 per cent of its nicotine content after 19 months, 
while the sample with 2.02 per cent nicotine lost during the same 
period over 80 per cent of its nicotine. The maximum loss from 
