ABSTRACTS 
On the Effect of Complete Anemia of the Central Nervous 
System in Dogs Resuscitated after Relative Death. D. H. 
Dolley and George Crile, M. D.* Jour, of Expe. Med., vol. 10, 
Nov. 1908. 
This study of brain anemia is the sequence of provious work on 
the resuscitation of animals killed by anaesthetics and asphyxia,* 
which may be briefly summarized as follows : By measn of a cen- 
tripetal arterial infusion of salt solution under sufficient pressure, 
together with the injection of one to two cubic centimeters of 
1-1,000 adrenalin chloride in mass dose early and along with the 
infusion, and the simultaneous employment of vigorous artificial 
respiration and gentle but firm cardiac massage through the 
unopened thorax, a heart which has ceased to beat maybe excited 
to resume beating within certain limits. Up to five minutes of 
total cessation of function, these efforts are uniformly and readily 
successful, provided that the full technique has been used: up to 
ten minutes, there is an occasional failure, but after that the 
chances of success become progressively less. Our limit was 
five minutes in puppies (three cases). 
To determine the limits of recovery after the total anemia of 
the central nervous system incident to a state of relative death, a 
series of thirty dogs was killed by chloroform and resuscitated 
after varying times from three to fourteen minutes. Under five 
minutes the recovery of function was rapid and strikingly free 
from the after effects which characterized longer periods. Of seven 
animals between the periods of five minutes and six and one half 
tFrom the Laboratory of Surgical Physiology, Western Reserve Univers- 
ity, and the Pathological Laboratory, University of North Carolina. 
2 Jour, of Exper. Med., vol. 18, p. 718, 1906. 
106 
[November 
