108 
Journal of the Mitchell Society 
[November 
indicative of cell death. Mavchi’s method further supported these 
findings by proving the existence of fibre degeneration. Finally, 
showing the narrowness of the escape, the best result in recovery, 
seven and one half minutes in time, which at the end of four 
iveeks had apparently entirely returned to a normal state, by the 
Marchi method had a degeneration of a number of fibres localized 
in the pyramidal fasciculi, which were traced from the cord to 
the cortex, and in Flechsig’s fasciculus, as well as a more sparsely 
scattered degeneration of both ascending and descending fibres 
elsewhere. The results of the histological examination place the 
limits of experimental resuscitation upon an anatomical basis. 
conclusions 
1. In dogs anesthetized by ether for preparation and killed 
quickly by chloroform, the average limit of total cerebral anemia, 
estimated from the cessation of the heart sounds to the return of 
circulation, which admits of recovery, is between six and seven 
minutes. Any recovery beyond seven and half minutes would be 
exceptional, and the ulterior limit appears to be under ten min- 
utes, hitherto stated as the most conservative figure after other 
modes of investigation. 
2. Further, experience with resuscitation of animals killed by 
anesthetics and asphyxia, embracing numerous unrecorded exper- 
iments as well as those forming the basis of the present article, 
establishes our former conclusion, that the procedures detailed 
afford a reliable method within its limitations, and certainly uni- 
formly successful within the limits compatible with the recovery 
of the central nervous system. 
Binders for Coal Briquets, % J. E. Mills. Bulletin 348 
of the United States Geological Survey. 
The bulletin contains a report of investigations made at the 
Fuel-Testing Plant, St. Louis, Mo., by the author. The charac- 
teristics of good briquets are discussed and the general conditions 
governing the use of binders. A very large number of different 
binders were investigated in the laboratoiy, the effort having been 
made to include in the list all binders which it was thought 
