THE LARKSPURS_AS POISONOUS. PLANTS. 8) 
‘-hours was added to the first and the whole shaken out with benzol. 
This, after taking up with acid water, was injected into the same 
guinea pig. The animal soon became very dull, walking with wad- 
dling gait when forced to move, being evidently affected by the 
poison. Two days later the animal was normal. The urine of a 
control rabbit, similarly shaken with benzol, produced no such symp- 
toms in this guinea pig. 3 
On February 11, 1907, an aqueous extract of 5 grams was injected 
subcutaneously into a rabbit weighing 666.14 grams. An hour and 
three minutes later the animal was unable to stand, and soon devel- 
oped convulsive movements of the limbs. This animal was expected 
to die at any time during the afternoon, but gradually improved and 
appeared slightly duller than normal the following day. On Feb- 
ruary 13 it weighed 613.61 grams; February 25, 595.29 grams; and . 
on March 16, 552.78 grams, showing a steady diminution in weight. 
An extract of 9.5 grams injected subcutaneously into a rabbit 
weighing 2,182.79 grams was without immediate effect. 
An aqueous extract of 20 grams when injected into a rabbit weigh- 
ing 481.93 grams soon caused paralysis of the limbs, and the rabbit 
died in 32 minutes. 
On February 11, 1907, a rabbit weighing 1,417.46 grams was 
opened under ether, and the mouths of the ureters were tied off, 
together with the bladder, to prevent elimination by the urine. An 
aqueous solution corresponding to 34 grams of the same plant was 
then fed by mouth. This animal remained dull all the afternoon, 
and at 4.45 p. m., 4 hours and 45 minutes after the feeding, he was 
resting with his chin on the cage. He was found dead and stiff at 
9.15 p. m., having evidently died some time previous. A post-mortem 
showed the ureters distended and sharply outlned. 
Another rabbit weighing 1,743.37 grams was prepared in a similar 
manner by tying off the ureters and bladder and was fed with an 
extract of 50 grams. In 1 hour and 47 minutes this animal was 
paralyzed and unable to stand, breathing very slowly, and died 6 
minutes later. The ureters were found dilated as in the previous 
case, and the stomach was slightly reddened. 
A control for these two rabbits was prepared in a similar manner 
at the same time as the others. Nine hours after the operation, when 
the two rabbits which were fed the Delphinium were dead, this rab- 
bit was bright and running about, but was then killed with chloro- 
form to prevent suffering. 
In these cases it is necessary to consider not only the effects of non- 
elimination but also the fact that the power which the liver possesses 
of storing up and removing injurious bodies from the circulation may 
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