RELATIONSHIP OF WHITE SKAKEROOT AND MILKSICKNESS. 9 



some of these autopsies was especially offensive and was compared 

 with the odor arising in mercurialism/' In one case the cerebral 

 ventricles contained fibrin and the brain itself was surrounded by 

 serum and pus. 5 The spinal cord in this case showed signs of in- 

 flammation. In other cases no special lesions were noted. c 



It was proved that many cases of milksickness were communicated 

 to man by means of milk and its products d or meat e obtained from 

 cattle affected with the " trembles " ; even the amount of cream 

 usually added to coffee is said to have induced the diseased Other 

 cases apparently arose without the products of diseased animals 

 being eaten, as by using contaminated water; g and, again, cases have 

 occurred in vegetarians. 7 ' In some cases the fencing off of the sus- 

 pected springs from the pasture was followed by the disappearance of 

 " trembles " from the neighborhood. The " trembles " still appear 

 at times, although much less common than formerly/ its disappear- 

 ance being traced to the cultivation of the soil ; j and it is associated 

 with certain shady, sharply localized, wet, untilled areas. No char- 

 acteristic geological peculiarity has been proved for these areas. A; 

 Drake met the disorder almost entirely on oak plateaus, and especially 

 on the so-called " slashes" or marshy areas. 7 It is claimed that the 



a Drake, D., 1. c, p. 172.— McCall, A., 1. c, p. 467. 



b Graff, G. B., 1. c, p. 363. 



c Philips, W. H. Milksickness. Cincinnati Lancet and Observer, vol. 20, p. 

 132, 1887.— Beach, 1. c, p. 137. 



d Drake, D., 1. c, p. 191.— Wilkinson, G. W. Etiology of Milksickness. North- 

 west. Med. and Surg. Jour., vol. 14, p. 156, 1857. — Townshend, N. S. Milk- 

 Sickness. Jour. Comp. Med. and Surg., vol. 4, p. 118, 1883. — Schmidt, C. H. 

 Milk Sickness. Cincinnati Lancet and Observer, vol. 20, p. 411, 1877. 



e Yandell, L. P. Report on Milk Sickness. Proc. State Med. Soc. Kentucky, 

 p. 94, 1868. [Gives negative reports.] 



f Graff, ,G. B., 1. c, p. 359. 



9 Crookshank, N. Observations on the Milk Sickness, Cincinnati, 1840, p. 11 ; 

 Sick Stomack, Ohio Med. Rep., vol. 1, p. 11, 1826.— Yandell, L. P. Inquiry into 

 the Nature of the Disease Called Milk-Sickness, West. Jour. Med. and Surg., 3 s., 

 vol. 9, pp. 383, 389, 1852.— Walker, J. W. Milk-Sickness. Science, vol. 8, p. 483, 

 1886.— Wilkinson, G. W., 1. c, p. 158.— Thompson, S. W. Milk-Sickness. West 

 Jour. Med. and Surg., 3 s., vol. 11, p. 480, 1853. — Jones, J. T. Short Essay on 

 Milk Sickness. East Tenn. Rec. Med. and Surg., vol. 1, p. 330, 1852-53. 



h Jones, J. T., 1. c, p. 329. 



* Connor, J. J. Further Contribution to the Subject of Milk-Sickness. Chi- 

 cago Clinic, vol. 17, p. 333, 1904. 



J Yandell, L. P., 1. c, p. 387.— Walker, J. W., 1. c, 540 ; also Trans. Indiana 

 State Med. Soc, 1873-75, p. 128. 



Note. — Some areas are not entirely freed by cultivation. 



fc Yandell, L. P., 1. c, p. 379. 



Note. — J. S. Seaton in his " Treatise on the Cause of the Disease Called by 

 the People the Milksickness," p. 10, claims that he can pick out milksick areas 

 by the geological conditions. 



1 Drake, D., 1. c, p. 184. 

 121 — i 



