— 116 — 



a result, our suspicion that the expression "guaranteed santalol-content" 

 ought not to be interpreted too strictly has been fully confirmed, inasmuch 

 as out of six samples of sandalwood oil not a single one stood the test 

 if (as has been our practice for years) the only accurate formula of 

 C15H24O is taken as the basis of the calculation. We give below the 

 result of our analyses: — 



No. 



di 5 o 



«D 



Acid 

 No. 



Ester- 

 santalol 



Entire 

 santalol 



Solubility in 70°/o alcohol 



1 



0,9785 



— 18° 



4,6 



2,4<>/o 



90,9o/o 



Sol. 1 : 5.2 vol. and more ; 

 turns turbid when highly 

 diluted 



2 



0,9782 



— 15° 18' 



3,0 



6,0°/o 



90,6 0/0 



Sol. 1 : 7 vol. and more with 

 slight opalescence 



3 



0,9766 



— 16° 58' 



5,3 



2,0<>/o 



90,9o/o 



Sol. 1 : 4.3 vol. and more 



4 



0,9751 



— 18° 37' 



4,3 



l,5o/o 



92,9o/o 



Sol. 1 : 4 vol. and more 



5 



0,9777 



— 18°5' 



5,4 



2,3o/o 



90,8°/o 



Sol. 1 : 4,5 vol. and more ; 

 becomes opalescent when 

 highly diluted 



6 



0,9715 



+ 0°5' 



1,? 



2,3o/o 



93,6 0/0 



Sol. 1 : 4 vol. and more 



It follows from the above that of the samples examined only No. 6 

 shows the guaranteed santalol-content, but the sp. gr. of this oil is so 

 low, and its rotation so abnormal, that it may be permissible to doubt 

 whether it was derived from Santalum album. Sample No. 4 approximates 

 to the guaranteed santalol-content, and in other respects also this oil 

 answers all requirements, but the remaining four samples are considerably 

 poorer in santalol and in part also leave something to be desired in other 

 respects, especially in point of solubility. The interest attaching to an 

 excursion into the conditions prevailing in the London market is increased 

 by a knowledge of the difficulties which are so often encountered there 

 by the honest manufacturer. 



B. O. Leubner 1 ) has also tested a number of sandalwood oil samples 

 in order to be able to form an opinion of the quality of the oils of 

 commerce and at the same time to determine in how far the latter answer 

 the requirements of the U. S. Pharmacopoeia. It is said that all Leubner's 

 samples were obtained from houses of repute. The values of ten oils lay 

 within the following limits: d§§ 0,951 to 0,974, « D — 9 to —19°, acid no. 

 1,07 to 5,48, santalyl acetate 1,45 to 3,34 °/o, entire santalol 90,1 to 99,6 °/o. 



!) Pharmaceutical Journal 84 (1910), 639. 



