— 73 — 



to their cineol content, we deem a note by Evans Sons Lescher $ Webb Ltd. 1 ) 

 to be of importance, in view of the fact that eucalyptus oils containing 

 phellandrene are there said to exert a pronounced irritant action when 

 their phellandrene content exceeds a certain proportion. 



Milke 2 ) recommends as a prophylactic against scarlatina, and also 

 as a remedy in the disease, rubbing the whole body of the patient from 

 head to foot, and immediately at the beginning of the affection, with pure 

 eucalyptus oil. The treatment is to be continued four days, and during 

 the first 24 hours the mucous membrane of the pharynx should be dis- 

 infected every two hours with a 10°/o carbolic oil. The treatment is said 

 to cure the disease and to prevent contagion. 



The second part of Vol. II of J. H. Maiden's work entitled "A cri- 

 tical Revision of the Genus Eucalyptus" 3 ), contains a description of the 

 following species of Eucalyptus, viz.. — Eucalyptus Raveretiana, F. v. iM.; 

 E.crebra, F. v. M. (Syn.: E. racemosa, Cav.; E. hmmastoma, D. C; E. graci- 

 lis, Sieb.; E. angustifolia , Woolls.; E. terminalis, Britten); E. Staigeriana, 

 F. v. M. (Syn.: E. crebra, F. v. M. var. citrata, F. v. M.); E. melanophloia, 

 F. v. M.; E. pruinosa, Schauer (Syn.: E. spodophylla, F. v. M.); E. Smithii, 

 R. T. Baker (Syn.: E. viminalis, Labill. var. pedicellaris, F. v. M. part.; E. Ma- 

 zeliana, Naudin.); E. Naudiniana, F. v. M. (E. multiflora, Rich.); E. sideroxylon, 

 A. Cunn.; E. leucoxylon, F. v. M. (E. gracilipes, Naudin) and E. Caleyi, Maiden. 



On the anthelmintic action of eucalyptus oil, see p. 121. 



Oil from Fagara xanthoxyloides. Some time ago, Thorns 4 ) in a 

 lecture before the German Pharmaceutical Society, reported on the root oil of 

 Fagara xanthoxyloides, Lam. (Zanthoxylum senegalense, D. C, N. O. Rutaceae). 

 The oil contained, besides dipentene, linalool and cadinene (?) a lactone 

 Ci 2 H 8 04 (m. p. 144 to 145°) called "Xanthoxin" by Thorns. The constitution 

 of the lactone is as yet unknown. It contains a methoxyl group and yields 

 a nitro derivative and a dibromide. When it is split up coumarinic acid is 

 formed. Thorns states that the body bears some resemblance to citroptene 5 ), 

 a compound which is also derived from a Rutacea, but citroptene has 

 two methoxyl groups and possesses a different elemental structure. 



Xanthotoxin is a fish-poison. When 5 mg. of it, dissolved in 0,5 cc. 

 alcohol, were added to water containing a fish weighing 0,6 K., the fish 

 immediately became semi-unconscious, then began to swim on its back, 

 and died after 2 honrs. 



The bark of the root as well as the fruit are used medicinally by the 

 natives of Togo. 



2 ) Analytical Notes 1910, January 1911. 



2 ) Monatsh. f. prakt. Dermatol. 50 (1910), No. 5. Quoted from Pharm. Zentralh. 51 (1910), 976. 



•'-) Comp. Report October 1910, 66. 



*) Chem. Ztg. 34 (1910), 1279. 



*) Apotheker Ztg. 16 (1901), 619; Comp. Report October 1901, 26. 



