- 142 - 



three are relieved, by the use of pollantin, and only in one case is the 

 Remedy ineffectual. 



R.Hoffmann 1 ), who ascribes hay-fever to hyper-sensitiveness against 

 pollen-albumen, thinks that the critical moment for the setting-up of the 

 pollen-irritation is when the glands from which internal secretions are, 

 separated are unduly active, and especially when there is hyper-secretion 

 of the thyroid gland. Hence he assumes that there is an analogy between 

 hay-fever and Basedow's disease. 



There is a passage in the paper by Hoffmann first referred to in which 

 the author describes the mode of action of pollantin in a manner which 

 appears to us to be capable of misunderstanding and in need of a brief 

 correction. After discussing ergotin and hydrastin he proceeds: "the 

 drawback of being too costly also applies to Moebius's Antithyreoidin, in 

 which, as in Pollantin and Graminol, I was able to detect the presence 

 of Adrenalin". It is true that the Monatsschrift fur Ohrenheilkunde states 

 that normal sheep-serum also dilates the pupils, and also that another 

 serum-preparation (which is obtained from the blood of animals that have 

 not undergone preliminary treatment with pollen-solutions and, according 

 to Dunbar, is free from antitoxin), may possibly have adrenalin added to 

 it in the course of the enriching-process which it is made to undergo. 

 But in so far as the passage may be held to indicate that our pollantin 

 may contain a similar admixture, we emphatically repudiate the suggestion. 

 Both the powdered and the liquid pollantin are pure serums, containing 

 no other additions than those expressly declared, the first being a mixture- 

 of almost equal parts of dry serum powder with sterilised sugar of milk, 

 the second the natural serum with an addition of 0,25°/o carbolic acid. 

 We have published these particulars from the first. If Hoffmann has 

 detected the presence of adrenalin in pollantin, this can be explained purely 

 in the natural way, and according to his own further statements it is to 

 be regarded as an advantage rather than as a drawback. But according 

 to all present experience the curative action of pollantin is due primarily 

 to the presence of true antitoxins. We may again point out that we do 

 not question Hoffmann's experimental results, but the conclusions which 

 he may possibly have drawn from them. 



Rose "Schimtnel § Co." (Red Rose). Although this unsurpassed 

 speciality has been so thoroughly introduced into all branches of the 

 perfumery-trade that recommendation of it is really superfluous, we desire 

 to point out once more that for the reproduction of a truly nature-like 

 fresh rose-scent our "Red Rose" has become literally indispensable. The 

 preparation incorporates this scent in its utmost perfection and, thanks 

 to its natural basis of extract from our German-grown roses, imparts to 



*) Berl. Klin. Wochenschr. 47 (1910), No. 42, p. 1926; Monatsschr. f. Ohrenheflk. etc. 44 

 (1910), No. 8; Zeitschr. f. Klin. Med. 169 (1910), Parts 3 and 4. 



