— 100 — 



Also that, when acted upon with ferrous sulphate, it forms the reaction- 

 products set forth in the subjoined structural formulae: 



H 3 C CH 3 



v 



CH 



CH 





CH 



CH 3 



"Glycolether". 



H 8 C CH, 





V 





CH 





CH 





HC<^ X CH 



OH 











H 2 C 



x ^>COH 



CH 





CH 3 







Glycol. 





Acoordirig to W. Salant 1 ), when American wormseed oil is given 

 to cats it acts first as a temporary excitant, and afterwards produces 

 general paralysis and coma. A dose of 0,2 cc. per kilo weight of the 

 animal, administered by the stomach, caused death within 24 to 48 hours. 

 The active constituent of the oil, ascaridol, acts nearly twice as power- 

 fully as does the oil itself, and reduces the blood-pressure. 



Wormwood Oil. Of the two varieties of this oil which remained 

 after the disappearance of the French article, that distilled by ourselves 

 fjom plants grown in our fields at Miltitz undoubtedly enjoyed the greater 

 demand, in particular because we were able, notwithstanding the unfavour- 

 able climatic conditions, to continue to offer at the previous price. Our 

 wormwood-plantations have tolerably well withstood the tropical heat and 

 the drought, and this year also have yielded two, albeit by no means 

 abundant, cuts. Therefore, unless an unforeseen demand should set in, 

 or perhaps some surprise should be in store on the part of the United 

 States, we intend to leave our quotations unchanged. In the United States, 

 however, the market has lately become much firmer, because almost the 

 entire output is said to have already passed into firm hands, and specu- 

 lators are doing their utmost to drive the prices upwards. The represen- 

 tative employed by our New York branch has ascertained the area under 

 wormwood in Michigan and Indiana to amount to 404 acres (as compared 

 with 395 acres last year) and the probable output to about 8000 lbs. In 

 Wayne Co., New York, 21 acres are cultivated with wormwood, their yield 

 being estimated at 370 lbs. As the world's consumption will need to be 

 satisfied with the above-named quantities, the price-prospects for American 



l ) Journ. of Pharmacology and experimental Therapeutics 2 (1911), 391. Quoted from 

 Therap. Monatsh. 25 (1911), 498. 



