— 37 — 



the fraction between 175 to 193 the limonene tetrabromide (m. p. 

 104 to 105 ) was prepared. From the physical properties the con- 

 clusion could be drawn that almost the whole of the terpene con- 

 sisted of 1-limonene. The aldehyde-content of the oil was 15,33 %; 

 the non-aldehydic portion of the oil was very aromatic, and with 

 this portion the ester determination was carried out, which, calculated 

 for the original oil, gave 8,6°/ ester-content. The geraniol- content 

 was 12,72 °/ . Baker and Smith accordingly give the oil of 

 E. Staigeriana the following composition: limonene 6o,o°/o> geraniol 

 12,72 °/ , geranyl acetate 8,32 °/ , citral i6°/ , indeterminable sub- 

 stances 2,96 °/o- 



L. P. Phillips 1 ) uses eucalyptus oil 2 ) with chloroform as a ver- 

 mifuge. The dose consists of 2,5 g. eucalyptus oil, 3,5 g. chloroform, 

 40 g. castor oil, which an adult takes in two portions. If depression 

 occurs already after the first half, the second half is not taken. Feeble 

 anaemic persons and children are given proportionally less. If ne- 

 cessary the dose has to be repeated every other day until the result 

 is obtained. The treatment was successful in 44 cases, and has this 

 advantage over the use of thymol, that it does not cause depression 

 of the heart. 



The therapeutic value of the two classes of eucalyptus oils, cineol 

 oils and phellandrene oils, is up to the present but little known. The 

 British Pharmacopoeia prefers that class of oils which is represented 

 by E. Globulus. Up to 1898 the oil of E. amygdalina was still rep- 

 resented in the British Pharmacopoeia. A case of poisoning due to 

 the administration of too large a dose induced F. A. U. Smith 3 ) to 

 ascertain whether the oil which had this injurious effect, contained cineol 

 or phellandrene. The faint yellow oil had the specific gravity 0,919 

 ( i 5j5°)? a D-j-4>47°, and when phosphoric acid (d 1,75) was added 

 formed a semi-solid mass with a red colour. 10 g. of the oil yielded 

 8,62 g. cineol phosphate, corresponding to 52,6 °/ cineol. The attempt 

 to detect phellandrene with glacial acetic acid and sodium nitrite gave 

 negative results. In the case in question, 6 fluid drachms (say 1-8 

 to 20 g.) of oil had been used, which quantity was sufficient to 

 cause death. 



A second case of poisoning with eucalyptus oil is the following: 

 A child aged 2 years 9 months 4 ) fell ill owing to having taken 



*) Ace. to Zeitschr. d. allg. osterr. Apoth.-Ver. 44 (1906), 177. 



2 ) Nothing is said as to the species, therefore Globulus oil is no doubt meant. 



3 ) Pharmaceutical Journal 76 (1906), 662. 



4 ) Brit. Med. Journ. of May 12, 1906. Accord, to Pharmaceutical Journal 

 76 (1906), 651. 



