— 104 — 



The products in question may only be forwarded in cases, boxes, 

 or bottles, which have been numbered and sealed by the officials, 

 and must be accompanied by a permit indicating the number, and 

 also the weight of the contents and the packing. 



The stocks in hand at the time of the publication of this Act 

 are already subject to these conditions. Contraventions are punished 

 with seizure of the products and severe fines, and in addition to this 

 an amount equal to five times the duty has to be paid. 



From Switzerland it is reported that similar measures are impending. 



For the detection of wormwood oil and oil of tansy in absinth 

 liqueur, L. Cuniasse 1 ) recommends various reactions which are all 

 based upon the detection of the thujone contained in the above-named 

 oils. We content ourselves with a reference to this work. 



Ylang Ylang Oil, "Sartorius'\ The demand has been so 

 brisk that we were compelled to ask our friends in Manila to make 

 a considerable increase in their production. We hope that we shall 

 now be able to meet the whole of the demand from the consumers. 



P. Kettenhofen 2 ) has studied the action of ylang ylang oil 

 (which we had placed at his disposal for the purpose) on micro- 

 organisms, colourless blood -cells, cold-blooded and warm-blooded 

 animals, and also the influence on the respiration-capacity and the 

 blood-pressure, and the action in normal and in increased reflex- 

 excitability, and has thereby arrived at the following results. Ylang 

 ylang oil injures, or destroys, micro-organisms, and prevents decay and 

 fermentation owing to its paralysing effect on the protoplasma of the 

 ferments of putrefaction and decomposition. Towards colourless blood - 

 cells it has an analogous action; the cells are paralysed, and unable 

 to leave the circulatory system, thus suppressing a commencing ulcer- 

 ation. In the organism of cold-blooded animals, ylang ylang oil causes 

 already in a small dose general paralysis, which with increased doses 

 ends fatally. In the case of warm-blooded animals, a passing diminution 

 of the functions occurs, which does not, however, cause any serious 

 injury to the organism. Pulsation and frequency of respiration become 

 less, breathing and blood -pressure more feeble; the animals show a 

 somewhat apathetic behaviour. In a reflex- excitability increased by con- 

 vulsion-producing poisons, the excitability becomes less when ylang 

 ylang oil is administered, and the convulsions cease. If it were desired 

 to transfer these results to man, no symptoms of any serious affection 

 would in Kettenhofen's opinion be produced, apart from those 

 already mentioned, if the doses were not too large. The normal reflex- 



*) Journ. de Pharm. et Chim. 25 (1907), 1 80. 

 2 ) Thesis, Bonn 1906 



