— Ill — 



means of thiosinamine. The first case was that of stricture in a five 

 years old child, caused by the accidental swallowing of concentrated caustic 

 soda lye. Before the thiosinamine treatment, it was impossible to 

 enter the stomach even with the finest probe; but after the second 

 injection the cicatrised tissue had already become so much relaxed, 

 that a flexible 3 mm. probe could be introduced. After the seventh 

 injection even a 0^/2 mm. probe could enter without difficulty. The 

 cure was complete. In the second case it was a question of a 

 stricture caused by inadvertently taking concentrated potash lye, 

 through which previous to the treatment only a 2 1 j 2 mm. probe 

 could pass. Here also, within a few days from the commencement 

 of the thiosinamine treatment (injection of 1,0 to 1,5 in the skin of 

 the back, in the vicinity of the spine), a relaxation of the cicatrised 

 tissue became apparent, so that a 6 mm. probe could pass through 

 it. An improvement in the general condition (cessation of vomiting, 

 increase of appetite) continued, with a considerable increase in the 

 weight of the patient, and finally a 10 mm. probe could easily pass 

 the cicatrised place. Four months after the treatment commenced, 

 the patient had completely recovered. 



Thymol. No change has come into the prices of the raw 

 material during the summer months, and the absolutely senseless 

 price-cutting, which has now for a long time rendered the thymol business 

 a source of disgust to every manufacturer with commercial ideas, 

 continues unabashed. Although there has been no lack of attempts to 

 raise the value of this article, the position of the crude material, as 

 already stated, has not assisted these movements, and up to the present 

 they have remained without result. 



Notes on recent research work concerning 

 terpenes and terpene derivatives. 



General. 



Whilst the nowadays generally accepted formulae for the principal 

 terpene derivatives, such as camphor, pinene, and numerous other 

 compounds, owe their origin and confirmation to the difficult work, 

 extending over years and even decades, of many investigators, 

 G. Wendt 1 ) considers it his duty to draw up new formulae for the 

 whole of the terpene compounds, which he bases, without any ex- 

 perimental foundation, entirely arbitrarily, and with a sovereign disregard 

 of all previous labour, upon a "pure" carbon atom, that is to say, 



l ) Pharm. Ztg. 52 (1907), 33 *■ 



