— 137 — 



As regards antiseptic action, para-thymol does not appear to be 

 inferior to the natural product, but ortho-thymol is only half as 

 effective. 



In order to form an opinion as to the possibility of employing 

 thymol as a remedy for intestinal worms, the author has experimented 

 with such worms (anchylostomum), but here also he found ordinary 

 thymol to be superior to its isomers, while ortho- thymol had the 

 least powerful effect. 



In respect to therapeutic efficiency the natural product appears 

 from this to be superior to both isomers. 



L. Balbiano 1 ), by treating anethol with acetate of mercury, had 

 prepared two glycols of anethol from which, by dehydration, he 

 obtained a hydrocinnamic aldehyde. On the other hand, Tiffeneau 

 and Daufresne 2 ) alleged that by treating one of the glycols with 

 2O°/ sulphuric acid they obtained anise ketone. Balbiano now, in a 

 fresh paper 3 ), declares that, contrary to the experience of Tiffeneau 

 and Daufresne, he obtained by an experiment carried out in the 

 same way, from both glycols (the a-glycol, m. p. 62 to 63 ° and the 

 /^-glycol, m. p. 114 to 1 1 5°) the same p-methoxy hydrocinnamic 

 aldehyde (b. p. 136 to 137 at 10 mm. press.; semicarbazone, m. p. 175 

 to 1 7 6°). In addition there was formed a small quantity of a com- 

 pound (m. p. 181 to 18 2°) to which, from its behaviour, the followiug 

 formula is assigned: — 



CH 3 OC 6 H 4 CHCH 2 CH 2 



I I 



o 



1 I 



CH 2 CH 2 CHC 6 H 4 OCH 8 

 For details, we refer to the original paper. 



With regard to the occurrence of i-allyl-2, 3, 4, 5-tetramethoxyben2ene 

 in French oil of parsley, see p. 73. 



Acids* 



The ketone C 7 H 10 O 4 ) which was obtained by Wallach by the 

 oxidation of zl 1 -cyclohexene acetic acid or zP-methylcyclohexene and 

 which, upon further oxidation, yielded glutaric acid, the nature of which, 



*) Comp. Report April 1900, 99. 



2 ) Compt. rend. 144 (1907)* *354; Report October 1907, 169. 



3 ) Rendiconti della R. Ace. dei Lincei 17 (^1908), 259. We quote from a 

 copy kindly sent to us. 



4 ) Liebig's Annalen 343 (1905). 53; 353 (1907), 292; 359 (1908), 308 

 Report April 1906, 128; October 1907, 177; November 1908, 197. 



