

128 Report of Schimmel § Co. 1922. 



Of odours of vegetable origin showing a sedative action, the author enumerates 

 the lily, lily of the valley, carnation, orange, opopanax, vanilla, and heliotrope. Various 

 blossoms, such as the lily, tuberose, and honeysuckle, are known to exercise a stupefying 

 action; by experimenting on animals the essential oils were proved to possess, with 

 the living organism, a similar action as chloroform or ether 1 ). 



Sores of various kinds have been treated in sixty-eight cases successfully with 

 terpeneless oil of lavender 2 ). If the greater part of the infected sores show no inflamma- 

 tory symptoms after several applications of the pure oil, it is then desirable to resort 

 to weaker solutions (1 to 10 per cent). Gangrene was arrested immediately,, and in many 

 instances cicatrisation was complete in less than a month. In the case of varicose 

 ulcers in particular, a weak solution has proved an excellent antiseptic. Very good 

 results were obtained particularly with burns and scalds by the application of the 

 terpeneless oil for four or five days, followed by wet dressings during four or six days, 

 and finally dressing with starch powder or bismuth. In the case of chancrous sores, 

 the pure oil was applied, and then a powder of thymol iodide and dry dressing. In 

 other cases, after removing the pus, the pure oil was injected and the sore covered 

 with a pad damped with the oil; this was renewed daily, and finally a dry dressing 

 applied after cleansing the sore. 



G. and K. Cori 3 ) report on the treatment of febrile tuberculosis of the lungs with 

 intramuscular injections of menthol -J- eucalyptus oil. The authors injected two to three 

 times a week 0.5 to 1.0 cc. of the following mixture: — 0.1 g. iodine, 0.5 g. camphor, 

 10.0 g. menthol, 10.0 g. eucalyptus oil, 20.0 g. castor oil, and give the result of the 

 treatment of 168 poor or indigent patients as follows: — (a) Patients with tuberculosis 

 of the second and third stage, as well as infantine tuberculosis, can in many cases 

 be freed from fever by means of Berliner's mixture 4 ), so that they mostly may undergo 

 a treatment with "alt-tuberculin" without contracting fever, (b) The suppression of 

 fever passes off lytically and without unpleasant consequences of any kind, (c) If 

 during a tuberculin-treatment continual fever occurs, injections according to Berliner 

 enable further application of tuberculin by depressing the fever, (d) Regardless of 

 the lowering of the fever, the subjective complaints, such as pain, cough, or night 

 perspiration, 8jc, were in all cases alleviated or even removed, (e) A rise in tempe- 

 rature after injections of tuberculin have no bad influence upon the action of tuber- 

 culin in the second stage of pulmonary tuberculosis, whereas in the third stage a rise 

 in temperature is generally associated with loss in weight, hemoptcea, §c. (f) The 

 fever-depressing action of the Berliner mixture passes off by action on the pulmonary 

 seat of the disease as being the cause of the fever. This was proved by experiments 

 which demonstrated that during the treatment with the Berliner mixture the cutaneous 

 sensitiveness towards tuberculine showed a decrease. 



As has been shown by Macht 5 )»the antispasmodic action of the combined opium 

 alkaloids is due to the presence of the benzyl nucleus in the alkaloids of the papa- 

 verine group. Simpler compounds containing the benzyl jnucleus, such as benzyl 

 alcohol, some of its esters, and benzaldehyde, but not benzoic acid, have the same 

 action. The antispasmodic properties are exhibited, as is demonstrated by H. A. Shoule 



*) Detailed studies on the after-effects on, and poisoning of, the olfactory sense have been published 

 also by Henning. Cf. Bepori 1916, 103. — 2 ) Marchand, Perftim. Record 12 (1921), 153. — 3 ) Therap. Halh- 

 monatsh. 35 (1921), 236. — *) Cori's recipe differs somewhat from the prescription given originally by Berliner. 

 — 8 ) Journ. of Pharmacol, and exp. Therap. 9 (1917), 287; 11 (1918), 263. 



