NOTES ON SCIENTIFIC RESEARCH. 125 
in the animal organism. Hamaldinen') has discovered that when the glucosides of 
certain terpene alcohols are injected subcutaneously, the corresponding glucuronic 
acids appear in the urine. The terpene alcohol could be detected neither in the 
blood nor in the organs, hence there had been no splitting-up of the glucosides into 
alcohol and sugar. On the other hand he found in the blood, in addition to the 
unattacked glucoside itself, the corresponding combined glucuronic acid, from which 
it was evident that powerful oxidation had taken place. 
Through the carefully washed-out small intestine of a rabbit narcotised with ether, 
Ringer’s solution was passed from the Arteria mesenterica to the portal vein, and glucose 
and a-santenol were injected into the intestine. After six hours irrigation the liquid 
which had been passed through and the contents of the intestine were tested for 
glucoside, when a substance was isolated which corresponded in every particular to 
a-santenol glucoside. It therefore appears that a glucoside formation from alcohol 
and sugar had in fact taken place in the wall of the intestine. 
J. Isaak?) has succeeded, by the intravenous injection of saturated aqueous camphor 
solutions, in provoking the typical, toxic action of camphor upon the central nervous 
system in the form of clonic spasms. In animals which have been narcotised the 
exciting effect of camphor is observable. In animals under the influence of chloral no 
increase of blood-pressure can be observed, but such an increase is shown in the 
case of animals of which the heart has been artificially weakened by subcutaneous 
injections of phosphorus. | 
On a case of poisoning after taking Oil of Pennyroyal, p. 76. 
Phyto-physiological Notes. 
At the meeting of the Philadelphia College of Pharmacy on October 17th, 1913, 
E. Charabot*) gave a lecture on the formation and distributation of the odoriferous 
principles in plants. In this lecture he reviewed his numerous researches‘) in the 
domain of phyto-physiology. 
In a paper read before the 11 International Congress of Pharmacy, held at the 
Hague in September 1913, E. Bourquelot®) gave a review of his Manuleeae ek in the 
domain of the glucosides. 
As we have regularly discussed Bourquelot’s publications in our Reports, a mention 
of his interesting paper may here suffice. 
I. Bolin®) has ascertained the presence in the leaves of Salix Caprea, L. of three 
glucosidases, viz. salicase, amygdalase and a (-glucoside-splitting enzyme. Their 
presence in the same Salix-species, however, is subject to variation from year to year. 
Thus, for instance, the $-glucoside-splitting enzyme, which was observed in one year, 
was absent the next from the leaves of the identical tree during the corresponding 
period of development. The author, by an experimental control-test, has also demon- 
strated that salicase is an enzyme with a specific action upon salicine. 
*) Skand. Arch. f. Physiol. 30 (1913), 187, 196; Chem. Zentralbl. 1918, II. 1319. — %) Pfltigers Arch. d. 
Physiol. 153 (1913), 491; Chem. Zentralbl. 1918, Il. 1419. — %) Americ. Journ. Pharm. 85 (1913), 550. — *) Comp. 
Report April 1900, 50; Orober 1901, 57; April 1905, 89; October 1905, 90; April 1906, 104; October 1906, 106. — 
aig Cea et Chim. VII. 8 (1913), 337. — 8) Zeitschr. f. physiol. Chem. 87 (1913), 182; Chem. Zentralbl. 
