NOTES ON SCIENTIFIC RESEARCH. vg | 
Copaiba balsam and copaiba balsam oil with reference to gonorrhoea. 
R. Stockman!) deals with the action of copaiba balsam and copaiba balsam oil 
on gonorrhoea. He asserts that the balsam has scarcely any influence on the diseases 
but that the oil possesses healing properties. 
Turpentine oil in the treatment of wounds. 
As L. Lematte states’), turpentine oil is a valuable aid in the treatment of wounds. 
It is used especially as a tincture and as a serum%). The tincture is prepared by 
dissolving 0.1 g. of magenta in 10 g. of turpentine oil, to which solution 10 g. of 
alcohol of 95 p.c. and 10 g. of ether are added. In order to make the serum, 1.5 g. 
of turpentine oil are triturated in a mortar with 8 g. of sodium chloride, and boiled 
water is then added gradually to make 1 litre. On arrival of the patient at the hospital, 
a purulent wound is first treated for 15 minutes with an undiluted hydrogen peroxide, 
twelve volumes. Then it is washed out with a mixture of equal parts of hydrogen 
peroxide and the turpentine serum and dried with sterile compresses. All mortified 
tissue is removed with scissors and forceps, the cleaned wounds swabbed out with 
cotton tampons soaked in the tincture, so as to penetrate all the tissue. It is allowed 
to dry for several minutes, then covered with a compress of absorbent cotton soaked 
in the serum. No impermeable material should be used for covering this. The bandage 
is renewed daily, and the tincture is put on all the pale-looking places. The healthy 
tissue is of blood-red colour and needs only the dressing with serum. If the healing 
does not progress, the tincture is again used. The cicatrizing and antiseptic power 
of the tincture are far greater than those of iodine tincture, and its cost is negligible. 
For all surgical lavations, the serum is to be preferred to sterile water, as the hyper- 
tonicity of this delays the healing process. Fistulous wounds may be treated with 
strips of gauze soaked with the tincture. This liquid has the slight disadvantage of 
staining skin and linen. The stains should be rubbed with a sublimate solution (1: 1000). 
Seriously infected limbs, which endangered the EL SUS life, have been saved from 
amputation through this treatment. 
Therapeutical use of pinene ozonide. 
Oil of turpentine is an old sterling remedy against all affections of the respiratory 
organs, but has the disagreeable property to irritate the kidneys, when given in large 
doses. This is said not to be the case with pinene monozonide, or oxypinene, as 
B. H. Waters*) calls the preparation. It does not harm the kidneys at all. It possesses 
_all the valuable therapeutic qualities of pinene, acts, however, generally in a milder 
form, and is said to be of good service in the treatment of consumption. It is reported 
to act as expectorant in cases of dry, ineffectual cough and to cause in general a 
more abundant secretion of the glands, just the same as turpentine oil. In addition, 
it seems to stimulate both appetite and digestion. 
Pinene monozonide is formed by the action of dry ozonized air on pinene vapours. 
With reference to this we beg to mention the process worked out by A. S. Ramage’) 
for the oxidation of terpene compounds and the production of terpene peroxide. It 
is an improvement on the U. S. Pat. 710893 of the same inventor, and consists in 
1) British Medical Journal 1915, 11, 128; Chemist and Druggist 87 (1915), 156. — 2) J. Med. Chirurg. Pract. ; 
L’Union Pharm. 56 (1915), 229. As per Pharmaceutical Journ. 94 (1915), 801. — *) The name of serum is 
here used for a kind of physiological salt solution. — 4) Americ. Journ. Pharm. 87 (1915), 163; Pharmaceutical 
Journ. 94 (1915), 767. — *) U. St. Pat. 1097939; Chem. Ztg. Repert. 89 (1915), 104. 
