Sy on COU) OE a a 
\ oa ; 
PR PARATION AND > DRucs. 
phenyydeazone is Sena by boiling the alcoholic solution of thiocoumarin and phenyl- 
ydrazine in the presence of copper powder and nitrate of lead; m. p. 140°. 
a 
Crist y cH: CH CH: CH 
Gi os. Cr CH 
~ “\So—Cs Sco fer or eS 
(1) CS-Thiocoumarin (Il) 1-Thiocoumarin (Ill) 1.2-Dithiocoumarin. z 
(Thione-coumarin). s (Thiolcoumarin). 
A monograph on coumarins published by’ Simonis will be found discussed on 
page 87 of this Report. 
3 Heliotropin. In a paper by A. Kaufmann and R. Radosevic*) on the synthesis 
_ Of isoquinoline derivatives we find particulars on the preparation of piperonylacetone 
_ from piperonalacetone, a substance not known so far. A solution of piperonal (helio- 
- tropin) in acetone is emulsified with water and the emulsion, mixed with soda lye of 
40 per cent. strength. In this process piperonalacetone is formed, of the m. p. 107 to 108°. 
CH, Oz: C;Hs- CHO - a CHe. Oz: C,H: CH: ‘CH: CO: CHs 7 Leia 
Piperonal. Piperonalacetone. 
CH. O.:CegH3-CHe: CH,:CO-CHs 
Piperonylacetone. 
By shaking a solution of piperonalacetone with hydrogen under ordinary pressure 
in the presence of colloidal palladium piperonylacetone is formed (m. p. 55°; b. p. 164 
_ to 165° (12 mm)) which possesses a characteristic pleasant floral odour. 
In the same manner methylvanillin yields 3.4- dimethoxybenzalacetone (m.p. 91 to 920). 
Menthol. R. Meldrum?) has published a few notes on the melting and solidifying 
point of menthol. Menthol becomes solid below its normal solidifying point because 
of its colloidal state which precedes crystallization. The solidifying point varies as 
also the colloidal state is variable, the variation amounting to 3.3° when using reliable 
methods. The melting point, however, is constant. 
These observations are a further confirmation of our opinion expressed some time 
ago’) that the melting point is much more suitable for the evaluation of menthol than | 
_ the solidifying point. 
Musk. It is a well known fact that musk possesses an“enormously strong and 
lasting odour. Nevertheless it is possible, as was found by C. B. Bazzoni*) to render | 
_ musk odourless by exposing it for some length of time to a current of dry air. In 
an experimental way Bazzoni has proved this with an infinitesimally small quantity 
of musk. He allowed dry air to pass over a piece of musk weighing 1.32245 mg. for 
7 months, checking the weight from time to time, when decreases of 0.00318 to 0.00002 mg. 
“were” observed. The musk had gradually become odourless and the odour did not 
return even if the musk was exposed to moist air. In order to determine these in- 
- finitesimal weights the author used a special micro- weighing balance of which he 
_ gives a short description. 
That the odour of musk would disappear after some time was to be expected, for 
we have proved long ago that the odoriferous constituent of musk is volatilizable with 
2) Berl. Berichte 49 (1916), 675. — 2) Chem. News 411 (1915), 229; Chem. Zentralbl. 1915, HI. 540. — 
2) Report April 1914, 105. — 4) J. Franklin Inst. 80 (1915), 463; Jowrn. Chem. Soc. 108 (1915), I. 1067. 
” 
