= ety a wet : ‘ IN a age 
BS yee 
e Copaiba Balsam. As to Columbia copaiba ‘balsam; See page 20 of this Bogert 
rs E Commarin. HL J. Wichmann’) Has wanted out the following feted for detecting 
and Beiseaiathe coumarin in artificial extracts of vanilla: 10 cc. of the extract are made 
Ba ino of ether. . -In case -the ethereal extract is feebly coloured, it is shaken with some 
I Be heers evaporated the residue is melted over an open flame. If coumarin is present, 
extracted with 5 to 10 cc. of benzene. Benzene is to be’ preferred to other solvents 
‘be cause of its lesser density, its lesser dissolving power for mineral acids and because 
Protocatechaic. acid, which is formed out of the vanillin that may have been dissolved 
‘the ether, is insoluble in it. The benzene solution is washed with a little water, 
filtered and tested with 1 or 2 cc. of dilute ferric chloride solution for salicylic acid. 
Tf If there is no turbidity, one neutralizes with N/10 soda lye the traces of mineral acid 
t hat might prevent the colouring. - nae ene | | 
_ In order to determine quantitatively the coumarin in ne extracts, 50 cc. ve the 
extract are treated with lead acetate, without removing the alcohol. ‘One then fills up 
to 100 ce, filtrates and precipitates the excess of lead with dry potash oxalate. 50 cc. 
free the extract from the vanillin, a ‘small quantity of phenolphtalein solution is added 
ater in each case, until the red colour disappears. The washed solution, which con- 
tai ns the coumarin, is Ne ie ae and ule residue dried and weighed. 
/ 
Pr acalyptole. Generally speaking aha like bodies are’ Laatinaiy soluble in water, 
of this oxide in water. He found that / 
ee aes at 1,5° 0,64 g. cineole dissolve in 100 g. water 
AG Ds (Sau As Thee fe Le 100 g. Ses 
LAPS! 10° Bas es.) i OS A pie 
jen f aXe @ s “ee PRPS 0,35 g. oy 3 ” : ” 100 g. Bi oy bo 
So ESE SOUS Vref aes ik Une iti ORs ean ist 19) 0 Beara Se 
4 sa ” 50° 0, 19 g- ” fi ” ay 100 g. _ devia 
_ According to these pas the solubility of cineole would decrease with ising 
mperature. VRE: | 
The. same author ronars on die sensitiveness of the well: known oulnle method for 
pr proving the presence of cineole. He heated 1 cc. of cineole with varying quantities of 
andrene and with iodole in a testing tube and filtrated the mixture on to a watch 
glass. With a dilution of 1 part of cineole in 3 parts of phellandrene, the iodole double 
Bround separated immediately, with a proportion of 1:10 after a short while and 
Bi PEOpertion: of 1:20 or os after half any hOUpe co" ‘ 
A 
= ~*~ 
Ee; Fiijuoh Industr. and Engin. Chemistry 10 pacha 535 ; Chem. Zentral. ‘118, Ul. 10ST. 6 Ss 2) Journ. Soe. 
ts “gM 37 cap tks 274 T. 
5* 
kaline . -with 10 per cent. soda lye, diluted with 16 cc. of water and extracted with 
2 c. ‘of concentrated alcoholic potash lye and washed with 19 cc. of water, thus elimi-. 
nating all organic acids, vanillin, colouring matter or saccharin. Then 1 cc. of 50 per . 
sent. potassium hydroxide solution is added to the ethereal liquid and after the ether 
there is a greenish-yellow flame when the melting begins, but which suddenly disappears 
‘on further heating, a sign of the coumarin having been ‘converted into salicylate. The 
r nelted substance is dissolved in a few cc. ‘of water, acidulated with sulphuric acid and — 
and alcoholic potash lye in excess. Then it is washed several times with 10 cc. of 
~ 
of "the filtrate ‘thereof are extracted with ether, benzene or chloroform. In order to 
vt ich is the case too with eucalyptole icneqle)- I. C. Earle a getenmted ne atlas ni 
