ee eh Chen AL F elaine AND ) Drugs. My on 75, 
_Terpineo AS ouite+) made ran. Shecriauan regarding the storing of chloroform 
r NZ arcosis, which may be very valuable but strongly requires verification. He found 
the inactive terpineol has. the property of protecting chloroform against physical 
f ohicthical influences (light, oxygen, water) which may bring about changes in its 
>on Be restitcn. No decomposition products could be found in pure chloroform containing 
; s than 1 per cent. of terpineol. Their formation had either been prevented altogether, 
ee had combined with the terpineol. The chloroform remained stable, even if 
red under the most unfavourable conditions, e.g. in unstained grees: in bottles only 
tly poled. and even in the presence of water. ee 
7 f 
By 
o Sake Monarda punctata,'L., a labiate, belongs to the plants that might be 
used with success for the manufacture of thymol. It has been tried already to cultivate 
it in the United States?) and in Montserrat3). The oil, distilled from the (green?) leaves 
wi ith a. yield of 9.27 per cent., was of lemon-yellow colour and had the following 
properties: di<5 0.928, ap — 1°66'(2!), np2so 1.501. It contained ‘60.4 per cent. peal 
from which 44 per cent. of crystallized thymol could be separated. 
ES Ajowan oils, distilled from seed also grown in Montserrat (yield 2.7 to 3.1 per ey 
of air-dried seed), showed the following constants: d=; 0.91 12 and d1500.925, &p 1°66'(2!) 
ind + 0.90°, phenol content 47.3 per cent., thymol content 43.5 and 54 per cent. 
a \ oil from St. Kitts showed d-“°-0.922 and a phenol content of 53 per cent. The 
optical rotation could not be ee owing to the dark colour of the oil. 
- 
x 
As to further trials of growing ajowan in the Seychelles and. Montserrat, see page 5 
f this Report. «3 ; Rd ears eae 
= <Some time ago, in a publication on the sulphonephthalein ranges of indicators 
and the quinone phenolate theory, H. A. Lubs and S. F. Acree*) described among 
ott er subjects the preparation of thymol sulphonephthalein. This body is obtained on 
melting for four hours a mixture of thymol, sulphobenzoic acid chloride and zinc ~ 
chloride at 140° and under frequent stirring. After recrystallization from alcohol, the © 
thymol sulphonephthalein forms greenish crystals. Its very dilute acid solutions are 
yellowish, the concentrated ones reddish, whereas the basic solutions are deep blue 
| the reflected and deep red in the transmitted light. Three to six drops of a 
0.0 per cent. alcoholic solution give, according to A.B. Clark and H. A. Lubs’), a 
good indicator for acidimetric and alkalimetric titrations. They mention as examples — 
ie titrations of mixtures of benzoic and hydrochloric acids, acetic and hydrochloric 
a acetic and sulphuric acids and of aniline with hydrochloric acid. It is true, the 
titration is possible only with certain concentrations, further relative particulars being 
ven in the original. 
w. Zinn®) mentions that thymol is praised from various “quarters as a remedy 
against trichinosis. It is given in doses of 0.5 g. every two or three alta 
ED --Vanitiin. Adulterations of vanillin with antifebrine, formerly observed repeatedly, 
lave now become very scarce. A sample Focrived nem Hemoate proved, however 
1) Rép. de Pharm.; Pharm. Weekblad 56 (1919), 189. iae! per Apotheker-Ztg. 84 (1919), 76. — *) Comp. 
C. Hood, Bulletin No. 372 of the U. S. Dep. of Agric.; Report October 1917, 100. — 3) Perfum. Record 10 
1919 19. — +4) Journ. Americ. Chem. Soc. 88 (1916), 2772; Chem. Zentralbl. 1917, I. 813. — 5) Journ. Americ. 
hem. Soc. 40 (1918), 1443. — *) Therapie der Gegenwart 1919, 81; Therap. Monatsh. 38 (1919), 233. 
y ‘ 
