I I 1 



PN-3664 



Plaques formed by foot-and-mouth disease virus particles 

 in tissue culture cells. 



Other Diseases 



Isolated vesicular stomatitis virus from an 

 infected human being. 



Developed a rapid laboratory diagnostic test 

 for African swine fever, in cooperation with the 

 East African Veterinary Research Organization. 



In cooporation with the same group, estab- 

 lished methods for growing the schizont form of 

 East Coast fever parasites in cell cultures. This 

 technique modifies the parasite for potential use 

 in a vaccine. 



Developed, in cooperation with the East 

 African Veterinary Research Organization, diag- 

 nostic tests for contagious bovine pleuro- 

 pneumonia in formalized lung tissues using 

 fluorescent antibody and agar gel diffusion 

 techniques. 



Purified the attenuated duck enteritis virus 

 and developed a seed virus, which was supplied 

 to the duck industry for production and use as a 



vaccine. This work was made possible by co- 

 operation of Dutch scientists who supplied the 

 starting materials. 



THE CENTER'S FUTURE 



As the world human population increases and 

 the food supply becomes less abundant for each 

 individual, the need to reduce losses from animal 

 diseases becomes more important. The Center 

 already has found and will continue to find new 

 ways such as rapid diagnostic tests, control 

 measures, and vaccines to limit or prevent 

 outbreaks of foreign animal diseases. 



Increased demand for food supplies involves 

 developing faster growing and improved types of 

 livestock, which in turn requires importation of 

 animals and semen with the special genetic 

 background to develop inbred and hybrid pro- 

 geny of the desired type. Here again the Center 

 is called upon to develop sensitive tests for 

 detecting disease agents so that such importa- 

 tions may be made with a minimum of risk. 

 Thus the Center has an important role in the 

 development of future food supplies from live- 

 stock. 



Basic research at the Center should continue 

 to develop new techniques and concepts. How- 

 ever, applied research will receive more emphasis 

 than it has in the past to put into service the 

 improved techniques and findings that have been 

 made through basic studies. Also, the results will 

 have application to many other branches of 

 medical science. 



The very nature of research prevents the 

 prediction of the exact character and the timing 

 of conclusive results, but achievements of the 

 program already have been outstanding. In the 

 years ahead, the Plum Island Animal Disease 

 Center undoubtedly will continue to add to the 

 achievements of U.S. and international research. 



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