THE DEVELOPMENT OF THE NERVOUS SYSTEM. 485 
‘ The ganglio-genetic cells, which at first are few in number, 
increase and multiply, without, however, changing their char- 
acter, and always remaining disposed in a single layer. 
‘In the seventh stage these cells cease to produce elements 
similar to themselves, and give rise on their deep surface to 
much smaller elements very poor in protoplasm, with nuclei 
easily stained by carmine which may be designated as ganglion 
cells; as soon as these are formed they themselves multiply 
very actively. Owing to this multiplication, the first proto- 
cerebral lobe becomes a mass of cells convex externally and 
concave within. 
‘It consists, then, of two layers of cells which are very 
distinct, a superficial layer on its convex surface of ganglio- 
Fic. 63.—A sagittal section through the outer part of the hemisphere of the adult 
larva showing the invagination of the mantle layer from which the retina of the 
imago is developed. d, invaginated layer surrounding the retinal rudiment ; 
e', epithelial mantle layer ; f, part of the pyramidal ganglion ; /, superficial cells 
of the optic ganglion ; 0, central stroma of optic ganglion ; /, group of small 
cells invaginated in the cavity of the rudimentary retina. 
genetic cells and a deeper portion consisting of numerous 
layers of ganglion cells.’ 
So far Viallanes’ description appears to be extremely clear, 
and to correspond closely with the phenomena observed in the 
Blow-fly by myself. It is possible that the deeper layers of 
cells are formed from the mantle layer. 
In two regions I have seen appearances which seem to 
