Table 11. — Maximum weight of rats fed various diets, sacrificed before or o 



fter 500 



days of age 





Sacrificed at 300-499 days 



Sacrificed at 500 days or over 



Strain and diet 



Rats 



Average 

 age 



Weight 



Rats 



Average 

 age 



Weight 





Average 



Range 



Average 



Range 



BHE rats 

 Stock . ._ . ._. 



Number 



31 

 52 



131 

 20 

 19 

 26 



16 

 6 

 6 



4 

 9 



8 

 7 

 6 

 5 



8 



29 

 6 

 4 

 2 

 6 



4 

 3 



6 

 1 

 3 

 5 

 8 

 14 

 5 



1 

 2 

 

 1 



1 

 2 





 3 



Days 



416 

 380 



392 

 408 

 410 

 394 



419 

 412 

 398 

 408 

 412 



408 

 416 

 402 

 377 



394 



409 

 429 

 416 

 394 

 409 



454 

 456 



429 

 459 

 407 

 420 

 451 

 402 

 430 



420 

 396 



Grams 



470 

 602 



626 

 684 

 615 

 680 



659 

 630 

 648 

 664 

 654 



661 



648 

 644 

 630 



645 



663 

 613 

 686 

 600 

 627 



651 



635 



633 



524 

 598 

 668 

 541 

 522 

 555 



537 



554 



Grams 



370-579 

 423-771 



456-790 

 575-791 

 486-800 

 510-976 



548-756 

 573-713 

 511-764 

 565-790 

 590-735 



605-723 

 568-856 

 536-765 

 510-740 



551-781 



565-780 

 550-684 

 630-766 

 597, 602 

 593-662 



571-736 

 501-845 



566-729 



524 



497-651 



582-744 



442-668 



448-698 



518-595 



537 

 530, 578 



Number 



57 

 57 



65 

 21 

 23 

 28 



8 

 3 

 3 

 4 

 1 



2 

 3 

 2 

 3 



2 



27 

 4 

 6 

 7 

 4 



15 



7 



4 

 6 

 7 

 5 

 17 

 6 



Days 



680 

 636 



575 



649 

 618 

 581 



584 

 566 

 562 

 570 

 508 



522 



552 

 578 

 535 



531 



611 



673 

 652 

 662 

 644 



696 

 689 



562 

 550 

 652 

 560 

 555 

 539 



Grams 



484 

 663 



645 

 753 

 690 

 715 



670 

 713 

 730 

 666 

 623 



624 

 660 

 665 

 596 



689 



709 

 676 

 675 

 645 

 624 



725 

 674 



687 

 574 

 692 

 666 

 541 

 589 



Grams 

 399-670 



SP8 HVO 



514-890 



Protein-fat-containing foods: 



SPE 



505-792 



SPM 



85-1,020 



SPB 



565-902 



SPPB 



610-908 



SPE supplemented with — 



Choline, 0.5% ... .-- 



583-790 



B12, 0.01 mg./lOO gm. . ________ 



666-780 



Choline, 0.5%+ B 12 , 0.01 mg./lOO gm. 

 B 6 , 0.5 mg./lOO gm . 



668-767 

 645-713 



Choline, 0.5%+ B 6 , 0.5 mg./lOO gm.. 

 Choline, 0.5% + B 12 , 0.01 mg./lOO 



gm. + B 6 , 0.5 mg./lOO gm 



Cholesterol, 0.46% 



623 



564, 685 

 544-820 



Cholesterol, 1.38% . 



627, 703 



Ascorbic acid, 0.2% _._. 



500-769 



Ascorbic acid, 0.2% + cholesterol, 

 0.46% 



600, 778 



Fat, 8% or 16%: 



SP 16 HVO 



593-875 



SP 8 lard 



627-722 



SP 16 lard 



599-797 



SP 8 butter . 



564, 732 



SPl6butter__ . _ 



528-700 



SP 8 HVO with protein or fat to level 

 of egg: 



SPa 16 HVO 



555-982 



SPb 8 HVO 



524-870 



Egg and egg fractions: 



SPE (fresh egg) 



566-788 



SPW 



440-668 



SPEW 



601-791 



SPEY 



590-763 



E100 



424-698 



Y100 



532-646 



Y97 + salt mixture, 3% . ... 





Diet reversal: 



Stock throughout life.. __ __ 



2 

 1 

 4 

 3 



9 



7 



9 

 5 



675 

 629 

 686 

 705 



772 

 791 



759 

 592 



612 

 825 

 694 

 680 



576 



758 



561 

 565 



528, 697 



SPE throughout life. . . 



825 



Stock changed to SPE at 250 days__ 

 SPE changed to stock at 250 days 



Wistar rats 



SP8 HVO 



608-791 



384 



446 

 355 



535 



445 

 538 



535 



445 

 519, 673 



643-709 



475-673 



SPE 



588-970 



BHE parents fed Wistar stock diet 



BHE young fed — 



SP8 HVO 



482-684 



SPE 



358 



533 



446-583 



510-616 







720-day-old animal fed SPM diet that weighed 

 1,020 grams. Among the rats 500 days and older 

 that were fed this diet, four reached weights 

 exceeding 900 grams. On SPPB diet, one rat 

 reached a maximum weight of 976 grams by 341 

 days, and three additional animals that were less 

 than 500 days old reached maximum 



weights 



exceeding 800 grams. No extremely large Wistar 

 rats were obtained with the semipurified diet, but 

 with SPE diet one rat weighed 970 grams at 750 

 days of age, exceeding by 178 grams the largest 

 BHE rat fed this diet. 



No quantitative data on body composition 

 were obtained for the studies reported in this 



21 



