TRANSPLACENTAL HOG CHOLERA INFECTION IN SUSCEPTIBLE SOWS. Stewart, W. C, Carbrey, E. A. and 

 KresseJ. I. Am. J. Vet. Res., Vol. 34, No. 5, May, 1973, pp. 637-640. (Abstract of Published Report) 



Susceptible sows in various stages of pregnancy were vaccinated simultaneously with attenuated or virulent 

 (Ames) hog cholera (HC) virus and anti-HC serum. Tissue specimens from offspring of the sows were examined for 

 HC virus by the fluorescent antibody cell culture technique (FACCT). Isolates from the newborn pigs and composite 

 suspensions of tissues that gave negative results by the FACCT were inoculated in susceptible pigs for confirmation. 



Transplacental infection occurred in four sows vaccinated with Ames virus and either 35 or 75 ml. of anti-HC 

 serum. The dose of antiserum and stages of gestation in which the vaccination was performed were factors that were 

 considered to affect the results of the experiment. These four sows were in the first month of pregnancy and three 

 of the four sows had been given the smaller dose (35 ml.) of antiserum. 



Transplacental infection was not confirmed in 12 sows vaccinated with attenuated virus and 20 ml. of anti-HC 

 serum nor in 8 sows vaccinated with Ames virus and either 35 or 75 ml. of antiserum. 



21 



