Compound 1080 has been-shovm to be very effective in controlling.field. 
: rodents. This operation is somewhat more complex than rat or mouse control 
and should be handled by organized crews under responsible leadership. ; 
As this chemical is Den our toxic to cats and dogs, persons exposing 
it for the control of rets should teke cars to remove these pets from the 
vicinity, so that they cannot find anc eat the treated bait itcelf or the rats 
or mice poisoned by it. A cat may be killed by eating a mouse that died from 
the effects of the poison. The hazard of secondary poisoning with 1080 is 
greater than with any other poison now in usee This e emphasizes the necessity 
of permitting it to be used only by qualified and experienced people. 
There is no knovm antidote for 1080 so the only safe way is to prevent 
all accidents. At the presont tims, first-aid treatment is limited to the use 
of emetics, and the poison must be eliminated within a few minutes. Cause the 
patient to vomit at ones*by tickling the throat with the finger or by giving 
+ teasponful of powdered mustard in 4 cus of warm water. Later give a dose of 
Epsom Salts as a purge. CALL A PHYSICIAN AT ONCE 
INSTRUCTIONS FOR THE PHYSICIAN 
(Chemical Warfare Service Recommendations) 
Compound 1080 affects the myocardium end the central nervous systems. In 
primates, the effect on the heart is the primary cause of death, Pulsus alter- 
nans appears first, followed by premature systoles and ventricular fibrillation. 
The reaction on the central nervous system is characterized by epileptiform 
convulsionse 
€ . Fy + 
1 
After the treatment to remcve the poison, put the patient at complete reste 
Control the central nervous system excitement by careful use of barbiturates 
having moderate duration of action, such es sodium amytal. Little else can be 
done to arrest the cardiac symptoms. If ventricular fibrillation should occur, 
the heroic treatment of injecting 5 cc. of a 1 percent procaine hydrochloride 
by intracardiac puncture will be justified in an attempt to restore an organized 
heart beat. 
Symptoms of 1080 poisoning usually subside within 12 to 24 hours. If any 
evidence of myocardium injury persists, however, keep the patient in bed for 
at least 3 dayse ; 
a 
NOTE [.=-taly one manufacturing company is now producing sodium fluoroace- 
tate (1080) in commercial quantities, and it limits the acceptance of orders 
to those from governmental agencies, as city, county, State, and Federal. af: 
organizations connected with roden't control, and to orders ant commercial 
pest-control firms. None is being sold directly to the general publice 
o- ~Compound. 1080 is a. new poison, and. the Wildli 
and. Wildlife Service, 546 coeen "Hous 
glad tor sceive reports of any eed experienc 
e Research Labora- 
NOTE 2 £ 
iD e, Denver, Colorado, would be 
6757. | 
