114 Dr.S.B.Schryver. Some Investigations Dealing [Aug. 12, 
univalent metals, and in salts of polybasic acids than in those of dibasic 
acids. The results here appended amplify those of the observers just 
mentioned, in that they demonstrate the influence of surface tension and 
viscosity on the solvent property. 
The solvent (or disaggregating capacity) was determined by titrating 
10 c.c. of a given suspension of the globulin with decinormal solution of the 
salt until the same solution grade was attained. The titration was carried 
out in a darkened room in a flat-sided trough, at the back of which 
was placed a constant source of light (electric lamp), the rays of which 
passed through a paper containing printed matter, held directly against the 
side of the trough nearest the light. The solution grade point arbitrarily 
chosen was that at which the printed matter was just legible through the liquid. 
The serum globulin was prepared in the ordinary way from horse serum. 
In Series I the globulin was purified by solution in ammonia, and 
precipitation from this solution by dilute acetic acid. 
In Series IT the sample was simply washed and the washings centrifuged off. 
Table 1V.—Amount of Decinormal Solutions necessary to add to Suspensions 
of Serum Globulin to Produce the same Solution Grade. 
Series I. Series IT. 
—— Strength of suspension | Strength of suspension 
2°74 per cent. 1°79 per cent. 
podium chloride =... 422-59. = 38 °5 
ey w DrOmMId eh. xy. eese. — 24 °5 
or le MOLLE LOR Soret 0 == 22 °8 
SiH OMI easy ce) seach ac ~— 16 ‘0 
>» Sulphocyanide......... == 15°5 
op OrmMate Wess. cross 47 -O 44 0 
5 lactate aril... Rake 48 ‘0 45 -O 
jo MUCRLALE ins cate rons 41 °0 43 °5 
»  monochloracetate ... 33 ‘0 34 °O 
»,  dichloracetate......... 22 ‘9 22 °2 
,,  trichloracetate ...... 17-0 14°7 
sn) benzoate 038. s3357.23 15 3 — 
ayy,» salicylate:..:. css jase 12°3 11 25 
wf) Imalonatel... ceva — 17 °5 
spun SUCCIMALCmar tin. on. cese == 21°0 
Sen AAT DPApC Me scores = 22 ‘0 
citmabe ers. ..n earns sss 11-0 
These results have been sufficiently discussed in the introduction. 
Edestin. 
A large number of determinations of the solubility of edestin in salt 
solutions have been carried out by Osborne and Harris.* The difference 
* © Amer. Journ. Physiol.,’ 1905, vol. 14, p. 151. 
