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Some Enumerative Studies on Malarial Fever. 
By Major Ronatp Ross, F.R.S., and Davip THomson, M.B., Ch.B., D.P.H. 
(Received October 12,—Read December 8, 1910.) 
Prefatory Note by Rk. Ross—Towards the end of last year the Advisory 
Committee for the Tropical Diseases Research Fund (Colonial Office) allotted 
considerable funds to the Liverpool School of Tropical Medicine for 
researches to be carried out in Liverpool. This enabled us to commence, 
under my direction, a number of minute co-ordinated studies on cases 
admitted into the Tropical Ward of the Royal Southern Hospital—material 
which, though it offered peculiar facilities for research, had long remained 
neglected owing to want of funds. The cases (occurring in the clinics of 
Dr. Macalister, Dr. Lloyd Roberts, and myself) were placed in charge of 
Dr. David Thomson; the chemical studies in charge of Dr. G. C. FE. 
Simpson; the parasitological studies in charge of Dr. H. B. Fantham. 
Parallel researches on animals were also assigned to Dr. John Thomson who 
is working under Sir Edward Durning-Lawrence’s fund for the investigation 
of the effect of temperature on disease; Dr. V. T. Korke (Research Fellow) 
has studied coagulation times and other details; the literature was in charge 
of Mr. W. R. Drawz, the Malaria Bibliographer (Advisory Committee’s 
Fund); and much valuable help has been given by the staffs of the 
University, the School of Tropical Medicine, and the Royal Southern 
Hospital of Liverpool, and by Sister Linaker of the Tropical Ward. 
The researches were commenced on January 1, 1910. <A paper by 
Dr. David Thomson and myself, describing a regular periodical increase of 
the trypanosomes in a case of Sleeping Sickness, was published ;* and we 
now present to the Society brief accounts of our results regarding malaria, 
blackwater fever, trypanosomiasis, and various therapeutical agencies, 
obtained (mostly by new methods) up to the end of July, 1910. Further 
details will be published, if necessary, in the ‘Annals of Tropical Medicine,’ 
Liverpool. 
1. Preliminary.—For many years past little information which is both 
new and exact has been added to our knowledge of the pathology of malaria. 
This has probably been due to the exhaustion of the older methods of 
research, which, being purely qualitative, have failed to indicate the precise 
correlations between the numbers of the parasites present in a patient and the 
various pathological and therapeutical reactions. For example, out of 
* “Roy. Soc. Proc.,’ B, July 21, 1910, vol. 82. 
