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1910. | System in Cured Human Trypanosomiasis. 237 
Four injections 2 ¢.c. atoxyl 20 per cent. December 6, 7, 16, and 17. 
18.12.06. Glands trypanosomes +. 
28.12.06. Glands trypanosomes —. Atoxyl 20 per cent., 2 c.c. 
29.12.06. Repeated atoxyl 20 per cent., 2 c.c. 
30.1.07. Glands trypanosomes —. 
8.2.07. Glands trypanosomes —. 
Condition.—Arsenical neuritis. Drowsy looking. Rheumatic pains. 
6.8.07. Condition far from satisfactory. Irregular fever, rapid pulse. Dull and 
stupid. Cervical glands enlarged. Trypanosomes not found in glands since March, 
1907. Energetic treatment with arsenic impossible owing to symptoms of poisoning 
rapidly appearing. 
15.2.08. Condition the same 6.8.07, but no trypanosomes found in blood or glands, due 
to the fact of taking mercury for syphilis (contracted 27.7.06). 
16.12.08. General Condition.—Strong, well nourished. No tremors. Reflexis normal. 
Gland puncture and blood examination trypanosomes —. 
Differential count. Lymphocytes 70 per cent. 
Some tendency to drowsiness when unoccupied. 
Last treatment, two injections kharsin, May, 1908. 
18.12.08. Proceeded to Mpumu to do duty with the Royal Society’s Sleeping Sickness 
Commission. Report by Sir David Bruce—“ This man appears to be in excellent health.” 
Returned to Entebbe. 
16.12.09.—Report by Captains Hamerton and Bateman, R.A.M.C., Sleeping Sickness 
Commission, Mpumu—“ No symptoms of Sleeping Sickness.” 
Blood Examination.—Examined peripheral blood. Negative results 14 occasions. 
Examined centrifuged peripheral blood. Results negative. 
Examined blood from median basilic vein. Results negative. 
Examined blood from median basilic vein centrifuged. Results negative. 
16.12.09. 4 ¢.c. blood from median basilic injected into monkey. 
29.12.09. 5 ae. oe Ms i - 
lst monkey examined 15 times. Results negative. 
2nd 99 99 12 bP) 99 oP) 
13.6.10. Lumbar puncture 17 cc. Cerebro-spinal fluid abstracted centrifuged. 
Trypanosomes —. No excess white cells. 12 cc. injected into monkey. Monkey 
examined twice weekly over one month. Results negative. 
General habits.—Intemperate. Had gonorrheea and syphilis. 
Post-mortem appearances 14 hours after Death. 
Body of lean but in no way emaciated man. 
Externally.—Cervical glands—small, hard, and shotty. Inguinal glands—small, hard, 
and shotty. 
Chest.—Parietal and visceral pleura adherent right side, due to recent pleurisy. 
Right Lung.—Weight 58 ozs. On section the whole lung was in a state of grey 
hepatisation. 
Left Lung.— Weight 14 ozs. Pleura and lung substance normal. 
Heart.—Weight 12 ozs. Right heart distended with blood clot. All chambers and 
valves normal. The glands at the root of lungs and around bronchi and trachea were 
enlarged and soft, and some were purulent. 
Microscopic.—Examination of this pus showed organisms resembling pneumococci. 
Liver.—Weight 89 ozs. Enlarged and congested. On section, soft and friable. 
Probably some fatty change. No obvious fibrotic changes. 
Portion preserved for microscopic examination in England. 
