1910.| Glossina palpalis Med on Sleeping Sickness Patients. 341 
Table I[1.—Transmission of Zrypanosoma gambiense from Sleeping Sickness 
Patients, Class A, to Healthy Monkeys, an Interval of Time being 
allowed for the Development of the Trypanosomes in the Fly. 
No. of | No. of No. of No. of 
- OF | Duration of | No. of | flies £ days flies | days flies 
eeeeoa se oat. | doses. | ies fed on| “¢09 on Parra Result. Remarks. 
ment. : | patient. . 
| patient. | monkey. — 
| 
1941 7 days 2 125 6 50 = Monkey remained 
. | healthy. | 
WS Ty, 2 100 6 50 oo é 
1969 1 month 4 | 100 Me 50 | - is 
1995 iy Ay i 13009 or 4 50 — - 
2240 | 2k years ? Gop emi adek: tl) ae °t50 = 
2952 | 22° a AT Ge = a 
| | 
Remarks.—Reference to Table II will show that six patients in Class A stage of the disease 
were under treatment. Two of these had been under treatment for one week, and had each 
received two injections of soamin, 0°01 gramme, combined with perchloride of mercury, 
0°02 gramme. Two had been under treatment for one month, and had received four injections of 
soamin, 0°01 gramme, and perchloride of mercury, 0°02 gramme, per dose. Two cases had been 
under treatment for two and a-half years: the total quantity of drugs received being, in one 
case, atoxyl, 16°2 grammes, perchloride of mercury, 2°4 grammes, and orpiment, 8°6 grammes ; 
the other case had received 18°8 grammes of atoxyl, 2°4 grammes of perchloride of mercury, and 
8°6 grammes of orpiment. 
Sleeping Sickness was not transmitted from any of these patients to monkeys by the flies. 
Two hundred and seventy-three flies were dissected between the 4th and 51st ake after feeding 
upon infected patients, but no flies were found infected with flagellates. 
Only one patient belonging to Class D was available for these experiments. 
This patient had been under treatment for one and a-half years, and had 
been treated with a total quantity of 13-4 grammes atoxyl, 0-4 gramme 
perchloride of mercury, and 6°5 grammes orpiment. 
Flies were not infected from this case, and the disease was therefore not 
transmitted to a normal monkey. 
