1910. ] Physiological Properties of Stovaine, ete. 415 
an inducement to arrive at some values. The following results were 
obtained in terms of water at 15°:—_ 
Table I. 
Salt. S.G. 15/15. Molecular weight. 
Methyl stovaine ......... 1°213, 257 °5 
Ethyl Pm. | 1-207, 271 °5 
Amyl reliable Sc stekerel eR 1 °106, 313 °5 
mipheny lier ide 5h eco 1°191, 335 ‘5 
Benzyl a errr 1 +178, 349 °5 
(The variation in the results obtained in the duplicate experiments was in the fourth 
decimal place.) 
It is evident from the above results that the densities, both for the 
paraffinoid and benzenoid derivatives, decrease with increase of molecular 
weight, but this decrease does not vary uniformly with each CH» group 
added to the molecule; the value of the amyl derivative is lower than 
that to be expected, but four determinations were made for the salt in the 
case of any error. 
- Affinty Value of the Base of Fourneaws Salt.—On account of the writer’s 
results as to the acidity of the salt towards indicators the hydrolysis and 
affinity values were determined by the methyl-orange method* devised by 
the former of us. The hydrolysis found was 1 per cent. at dilution 
V=4x103; hence the affinity value of the base K, can be calculated by 
Arrhenius’ dilution formula and Kohlrausch’s data for ionisation of 
water as 
K; = 0°99 x 4.108 x 4:9. 10745/(0:01)? = 7:9. 1078. 
The above value is comparable with that of glycine ethyl ester hydro- 
chloride = 9°7 . 1078, and also for such comparison the affinity values (as 
determined by the borax method) of cocaine, stovaine, and methyl stovaine, 
whose hydrochlorides show no hydrolysis, are given below :—f 
Base. K,.1077. 
Cocaine Prneae. osc. ccc accessoceees 4. 
Stovaine (base) ...........csee00 1°5 
Methyl stovaine (base)......... 3 °2 
* ‘Trans. Chem. Soc.,’ 1908, vol. 93, pp. 652, 2114, 2129. 
t ‘Trans. Chem. Soc.,’ 1909, vol. 95, pp. 763—766. 
