420 Physical and Physiological Properties of Stovaine, ete. 
Table IIL—Cf. Fig. 
, | 
Mean arterial pressure. | 
| Ratio of fall 
| 
| | 
OWeicht of Gee ss 
Drug. ne § to original 
; | animal, | Before |. After ieee. 
| injection. | injection. 
| | | 
| kgrm. mm. Hg mm. Hg. | Per cent 
Stovaine (9 °4 mgrm.).........ceeceeoeeaes 3°7 80 52 35 
Methyl stovaine ( ‘8 mgrm. ‘ ieetaceee 3°3 122 82 | 33 
Amy] stovaine (11 ‘1 mgrm.).........+6 2°8 176 108 39 
Fourneau’s new salt (9 ‘0 mgrm.)... 3:0 116 106 | 9 
i (13°5 mgrm.) .. 30 118 96 | 19 
These results are shown in the records—Fig. 1. 
The above doses of stovaine, methyl stovaine, and amyl stovaine are 
equimolecular to one another and to 116 mgrm. of Fourneau’s salt. The 
effect of amyl stovaine is perhaps exaggerated by the smallness of the 
animal. 
In short, on the central nervous system and on the circulation, Fourneau’s 
salt is less active, and methyl stovaine is, at most, no more active, than 
stovaine. On the central nervous system, amyl stovaine is less active; on 
the circulation, its depression is somewhat greater in degree, though more 
gradual in onset. 
These three bodies will be further investigated, on more nearly clinical 
lines, for the purpose of ascertaining whether their anesthetic properties 
may fittingly be employed in medical and surgical practice. 
