1910.] The Effect of some Local Anesthetics on Nerve. 427 
more sustained effect against the possible disadvantage of more ready precipita- 
tion of its base. 
Table V.—Amyl Stovaine. 
Time required to Duration of 
Concentration. Temperature. block maximal 
| Z block. 
| stimulus. | 
{ | 
aC: mins 
N/100 (0°31 per cent.) ......... 18 2°5 <2 hrs.: 
MOON pases ccctct ad cons ealvew essen. 19 3 < 24 mins. 
C500 deseeeha a er 17 *4 8°5 6 
Phenyl Stovaine and Benzyl Stovaine. 
The bases of these bodies are even more readily precipitated by alkalis 
than that of amyl stovaine. It was, therefore, impossible to examine them 
in tap water saline. In distilled water saline their effect resembles that of 
amyl stovaine in the relative slowness of its onset and subsidence. They 
appear to. offer no advantage over amyl stovaine. 
Table. VI. 
Time required to Diusati f 
‘Concentration. Temperature. block maximal hi, 4 Y 
| stimulus. ae 
Phenyl Stovaine. 
Bes mins. mins, 
N/300 (O°1 per cent.) ......... 19 1 >27 
IN/500 Bee cc eue Ope eral 5 
Serene cab, | 16 °5 8°5 1 
TE 3 inc | 18 °5 ss 7°8 <a 
Benzyl Stovaine. 
N/300 (0°12 per cent.):........ | Ney one tet 2 27 
IN/500 Beet ce 18 °5 | 4 55 
sy Sees Matec i aeteisetts citree's oe 15 ‘6 | 10 8°5 
Fourneaws New Salt. 
This body is one of the most active of the series. In rapidity of onset, 
and in duration, its effect is comparable with that of stovaine. As stated 
above, p. 418, it is relatively inactive on the central nervous system and 
on the circulation. It should therefore prove an admirable local 
anzsthetic. According to Fourneau (vide footnote, p. 414) its methyl 
homologue also possesses marked local anesthetic power. 
