vi Obituary Notices of Fellows deceased. 



the next day by, " Went with Harley and Wason to Bernard, who introduced 

 us to Majendie ! ! " ; on March 13, 1851, occurs the entry " Was with Bernard 

 performing several experiments." Among other entries scattered along the 

 diary are the following : " Performed operation for obtaining pancreatic juice on 

 a rabbit ; did not succeed in introducing the cannula " ; " injected a pigeon " ; 

 " operated unsuccessfully on a dog for pancreatic juice ; " " operated success- 

 fully on pancreatic duct," etc. A more elaborate note-book of this date in 

 his handwriting gives a synopsis of Bernard's experimental lectures, and 

 treats some subjects in much detail, notably, the role and nature of glycogen 

 and the phenomena of diabetes. He was in Paris during the exciting period 

 of the Coup d'Mat, December 2, 1851 ; in 1852 he came back to England for 

 Easter, but returned to Paris for May and June, mainly in order to finish 

 some of his chemical work. He had now decided to settle in London, this 

 resolve being largely determined by his approaching marriage with Ghetal 

 Herschell, the daughter of the Eev. K. H. Herschell, and sister of Farrer 

 Herschell, who subsequently became Lord Chancellor. In this union, which 

 took place in 1853, he found, in the highest sense of the word, the helpmeet 

 for him ; all who knew Sir John and Lady Burdon-Sanderson are well aware 

 of the peculiar strength of the ties which bound them, whilst those who 

 have enjoyed the privilege of more intimate friendship realise that the great 

 powers of the husband were fostered by the congenial atmosphere which the 

 devoted care and loving sympathy of the wife ensured. In the serenity of 

 true domestic felicity, a happiness which was to last without a check for over 

 fifty years, he started in London as a practising physician. His scientific 

 bent inclined him to take some scientific post if it should be offered him, 

 and, in recognition of his extensive knowledge and undoubted ability, such 

 offers soon occurred. He was in 1854 appointed Medical Eegistrar to 

 St. Mary's Hospital, whilst a little later he was made Lecturer in Botany, 

 and finally Lecturer in Medical Jurisprudence at the medical school attached 

 to this institution. In 1854 he contributed, among other things, a masterly 

 article on " Vegetable Eeproduction " to Todd's Cyclopaedia of Anatomy 

 and Physiology, thus showing that his botanical interests remained as strong 

 as ever. 



In 1856 there occurred an event which may be considered as the first and 

 greatest landmark in his scientific career, for it was the event which deter- 

 mined the specific character of his life's work ; in this year he was appointed 

 Medical Officer of Health for the extensive district of Paddington. That 

 a post of such responsibility should be offered to a man under thirty years of 

 age, and within three years of his arrival in London, is striking evidence 

 of the high opinion which had been formed of his powers ; these were now 

 to be successively focussed on those branches of medical science in which he 

 was to achieve acknowledged eminence. From practical sanitation he rapidly 

 became an authority upon the scientific aspects of hygiene, and this study 

 led by a natural extension to wider aspects of pathology, and ultimately back 

 to physiology. 



