1906.] The Relation of the Kidneys to Metabolism. 



77 



very susceptible to cold. They acquired a very foul breath, and soreness of 

 the lips and gums ; their fur came off very rapidly. 



Cat I lived six days, Gat II lived seven days, and Cat III lived 17 days 

 after the second operation. The rectal temperature was maintained at 100° 

 or more until the last few days of life. 



The Body Weight. — It will be seen from the following table that normal 

 cats lose weight when kept in confinement, notwithstanding some exercise 

 daily. The loss of weight, however, is less than that observed in Eose 

 Bradford's dogs, most of which lost 10 per cent, or more of their initial 

 weight before the first operation. In our experiments, the cats were not put 

 into the collecting cage before the first operation, so that this initial loss of 

 weight was avoided. 



Table I. 





Initial weight. 



Final weight. 



Loss. 



Time in cage. 



Normal cat 



grammes. 

 3650 

 2300 



grammes. 

 3580 

 2140 



Per cent. 

 1-9 

 6-9 



days. 



19 



8 





The effect of the two operations upon the weight of the cats is shown in 

 the following table : — 



Table II. 





Initial 



weight, first 



operation. 



Weight at 

 time of 

 second 



operation. 



Loss. 



Final 

 weight. 



Loss. 



Life after 



second 

 operation. 



Cat I 



grammes. 

 2420 



2880 

 2500 



grammes. 

 2120 

 2550 

 2220 



Per cent. 

 12 3 

 11-4 

 11-2 



grammes. 

 1600 

 1840 

 1640 



Per cent. 

 33-8 

 36-1 

 34-4 



days. 



6 



7 



17 



Cat II 



CatHI 





The final percentage loss of weight is much the same, and was reached in 

 Cat III in 17 days, and in a much shorter time in the other cats, because 

 Cat I ate well for 10 days, whereas the others ate very little after the second 

 operation. These figures correspond closely with those of Eose Bradford ; he 

 also found that the animals lived much longer after the second operation 

 when they took food. 



II. The Nitrogenous Metabolism. — The total nitrogenous metabolism was 

 determined in three cats before and after the second operation ; the urinary 

 nitrogen was also estimated in one of these cats before the first opera tiou. 

 The results are summarised in the following protocols : — 



