432 



Messrs. S.'G. Shattock and L. S. Dudgeon. [Mar. 18, 



Post nephric abscess. 

 Anaemia of unde terminal origin. 

 Pleurisy and pericarditis. 

 Septic bronchopneumonia. 

 Carcinoma of pylorus. 

 Sub-acute rheumatism, probably 

 gonorrhceal. 



Septic nephritis. 



Myxcedema. 



Hepatic suppuration. 



Ulcerative endocarditis. 



Pickets. 



Acute cerebro-spinal meningitis. 



Diabetes and lipaemia. 



In the case of some of these diseases more than one example was studied. 



List of Diseases in which Fat was found in the Leucocytes. 



Chlorosis. 



Chronic Blight's disease and 



anaemia of chlorotic type. 

 Carcinoma of* pylorus and 



anaemia of chlorotic type. 

 Influenza. 

 Pleurisy and pericarditis. 



Toxaemia of pregnancy. 



Acute pneumonia. 



Purpura. 



Diabetes and lipaemia. 



Myelaemia. 



Lymphadenoma. 



Acute cerebro-spinal meningitis. 



If these cases are analysed it will be found that most of them come in the 

 category of toxic diseases, some of an acute kind, others of a chronic. Of the 

 three cases of Myelaemia in which fatty degeneration of the finely granular 

 leucocytes was found, one was acute, two were chronic. 



The degree of fever present in these toxaemic diseases varied according as 

 the condition was one of intoxication or infection. In one of the most 

 pronounced examples of fatty change, viz., the toxaemia of pregnancy, the 

 pyrexia was very slight. 



In the toxic series may be placed : — 



Toxaemia of pregnancy. 



Acute pneumonia. 



Myelaemia. 



Purpura. 



Acute cerebro-spinal meningitis. 



Influenza. 



Pleurisy and pericarditis. 



Lymphadenoma. 



Chronic Bright 's disease (associated 



with some degree of chlorotic 



anaemia). 



In regard to this group of cases we believe that the fatty change present in 

 the finely granular polymorphonuclear leucocytes results from the direct action 

 of the toxic substances present in the blood itself ; that is to say, that the 

 change is one of proper fatty degeneration as distinguished from the ingestion 

 or storage of fat by a healthy cell. 



