582 Messrs. G. A. Buckmaster and J. A. Gardner. [July 19 ; 



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O i 2 34 5 6 7 '8 9 io n 12 13 14 15 16 17 18 19 20 zi 22 23 24 25 26 27 28 29 30 31 32 33 34' 



Minute? 



Curve A. — Constructed from Data given in Experiment I, 



Ordinates = milligrammes of chloroform in 100 grammes of blood ; abscissae = times in 

 minutes after the cessation of chloroform inhalation ; X = samples of arterial blood 

 (eleven). 



Experiment II 



Cat. Weight 3*5 kilogrammes. Eespiration recorded by tambour on 

 abdomen. Samples taken by a syringe from a long cannula introduced into 

 the external jugular vein, so that blood was withdrawn from the circulation 

 close to the right auricle. It was ascertained post mortem that this was the 

 case. The first cubic centimetres of blood withdrawn were rejected so as to 

 avoid taking a sample of stagnant blood in the vein. 











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I 2 3 4 5 6 7 8 9 IO II 12 15 14 15 io 17 18 19 20 21 22 23 24 -5 26 27 28 23 30 3* 3^ 33 34 35 36 37 3^ 39 40 41 



nubes. 



Curve B. — Constructed from Data given in Experiment II. 

 Ordinates = milligrammes of chloroform in 100 grammes of blood ; abscissae = time in 



minutes after the cessation of chloroform-inhalation 

 withdrawn close to right auricle. 



samples of venous blood 



Experiment III. 



Cat. Weight 3 kilogrammes. Samples taken simultaneously from the 

 carotid artery and from the central end of the external jugular vein. The 

 venous blood was withdrawn by a syringe from a cannula pushed down the 

 vein so that the blood was aspirated from the superior vena cava close to the 

 right auricle. The exact position was ascertained post mortem. In order to 

 obtain the sample as close to the heart as possible, the blood stagnant in the 

 vein was rejected. The details of this experiment are given in Table III, 

 from which Curve C was constructed. 



A number of other experiments were also performed, for example, some in 



