

1905.] | | Degeneration of Ova in the Rabbit. 267 
The substance which causes this change in the constitution of the blood, 
which creates disturbance and results in activity, is probably of the nature 
of a ferment. It affects similarly both male and female animals, and may 
be considered as a special “ generative ferment.”* 
As I have already shown, there is strong evidence that the increased 
activity of the generative glands, consequent on the presence of this 
“ferment,” results in the secretion of material which exercises a profound 
effect upon the rest of the generative system and possibly upon other organs ; 
for this secretion I will suggest the term “ gonadin ” should be used. 
LITERATURE. 
1. Barry, “ Researches in Embryology,” ‘ Phil. Trans.,’ 1839. 
2. Benecke, “Ueber Reifung und Befruchtung des Eies bei den Fledermausen,” 
‘Zoolog. Anzeiger,’ vol. 2, 1879. | 
3. Beneden, “ Recherches sur l’Embryologie des Mammiféres,” ‘Archives de Biol.’ 
vol. 1, 1880. 
_4, Beneden and Julin, “Observations sur la Maturation, la Fécondation, etc., chez les 
Cheiroptéres,’ ‘ Archives de Biol.,’ vol. 1, 1880. 
5. Eimer, “Ueber die Fortpflanzung der Fledermause,” ‘ Zoolog. Anzeiger,’ vol. 2, 
1879. 
6. Fraenkel and Cohn, “ Experimentelle Untersuchung ueber den Einfluss des Corpus 
Luteum auf die Insertion des Kies,” ‘ Anat. Anzeiger,’ vol. 20, 1901. 
7. Fraenkel, “ Die Function des Corpus Luteum,” ‘ Archiv f. Gynzekol.,’ vol. 68, 1903. 
8, Fries, “Ueber die Fortpflanzung der Einheimischen Cheiropteren,” ‘ Goéttinger 
Nachrichten,’ 1879. 
9. Gawronsky, ‘‘ Ueber Verbreitung und Endigungen der Nerven in den weiblichen 
Genitalien,” ‘ Archiv f. Gynekol.,’ vol. 47, 1894. 
10. Grusden, “ Versuche iiber die Kiinstliche Befruchtung von Kaninchen Eiern.,” 
‘Archiv f. Anat. und Physiol. Anat. Abtheil.,’ 1896. 
11. Hausmann, “ Ueber die Zeugung und Entstehung des Wahren Weiblichen Eies bei 
den Saugethiere,” 1840. 
12. Heape, “The Development of the Mole. The Ovarian Ovum,” ‘ Quart. Jourl. of 
Microscop. Science,’ vol. 26, 1886. 
13. Heape, “The Menstruation of Semnopithecus Entellus,” ‘ Phil. Trans.,’ 1894. 
14. Heape, “The Menstruation and Ovulation of Macacus rhesus,” ‘ Phil. Trans., 
1897. 
15. Heape, “The Menstruation of Monkeys and the Human Female,” ‘Trans. Obstet. 
Society,’ vol. 40, 1898. 
16. Heape, “The Sexual Season of Mammals,” ‘ Quart. Jourl. of Microscop. Science,’ 
vol. 44, 1900. 
17. Hertf, “ Ueber den feineren Verlauf der Nerven im Kierstock des Meuschen,” ‘ Zeit. 
f. Geburt. und Gynekol.,’ vol. 24, 1892. 
* T originally suggested ‘‘ cestrus toxin ” as a name for this disturbing agent, but, as its 
influence is not confined to the female, and as there is no reason to assume the presence of 
poison, this term is misleading. 
T 2 
