384 Goats as a Means of Propagatin of Mediterranean Fever. 
Examination of a Herd Supplying Milk to Slhema. 
Two goats were bought from this herd and placed in the lazaretto. The 
pens were in the neighbourhood of Misida. 
Goat No. 15.—On July 5 the blood was examined and the serum, diluted 1 
to 50, was found to cause complete agglutination of the IZ. melitensis visible 
to the naked eye. The goat appeared to be in good health, and the udders 
were full of milk. Some milk was withdrawn and 2 c.c. centrifugalised ; the 
deposit was then plated in the usual manner. On July 9 the plates were 
found covered with small colonies of the AZ melitensis. 
On July 6 the milk was again examined, and the deposit from 1 c.c. produced 
as before an immense number of colonies of M. melitensis. 
The urine was withdrawn by a catheter and plated on July 5, 6, 7, 8, 9, and 
10, but up to the present the JZ. melitensis has not been isolated. 
A chemical analysis of the milk was made by Dr. Micalef, with the 
following results :— 
Total solids, 13°5 per cent.; fat, 41 per cent.; ash, 0°75 per cent. 
Goat No. 16.—This goat was taken from the same herd as No. 15. On 
July 4 the blood was examined, and the serum diluted 1 to 60, was found to 
cause immediate clumping of the JZ. melitensis. The milk and urine have 
been examined daily since July 4, but up to the present the MZ. melitensis Has 
not been isolated from either source. 
Conclusions.—The results obtained show that some of the goats in every 
herd examined are suffering from Mediterranean Fever. The MM. melitensis is 
exuded in the milk in enormous numbers when the disease has been present 
sufficiently long to cause a change in the physical characters of the fluid. It 
is also excreted in considerable numbers even when the animals are in “full 
milk,” and no changes have occurred in either the physical or chemical 
characters of the milk. 
The M. melitensis is also excreted in the urine of goats suffering from 
Mediterranean Fever, but up to the present it has only been found when the 
disease has existed for some time and physical changes have occurred in the 
milk. 

