1905.] Pharmacology of Indaconitine and Bikhaconitine. 489 
G,, faradisation of nerve-muscle preparation slightly affected by 0°3 gramme per kilogramme 
pseudaconine (from indaconitine) for 3 secs. on each occasion. The time-interval 
(marked between stimulations) varies. A pause of 3 secs. before the last group. 
G., direct stim. of muscle. 
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contraction, the shorter and the fainter the response. There is a rest time 
of 3’ before the final group is taken. A single response to 3” faradisation 
recorded on a rapidly moving surface is shown (fig. H). 
H. Sinele faradisation (3 secs.) of nerve of above recorded on rapidly moving surface. 

The section on aconine in a previous paper* may stand for the pseudaconines 
now under discussion, in so far as the action of these upon reflex excitability 
of the cord, upon respiration, and upon the form of the muscle curve are 
concerned. All three appear to possess in common some antagonising action 
towards the weakening and incoordinating effect produced by the aconitines 
upon the frog’s heart. This circumstance is referred tof when the respective 
action of aconitine and aconine (from A. napellus) was discussed. 
* ‘Phil. Trans.,’ B, vol. 190, p. 380. 
+ Ibid., p. 283. 
