21 



Pa. The Initiation of Synthesis, Biological Stability and 



Mechanism of Formation of Adaptive Enzymes in Micro-Organisms . 

 To (1) study mechanism of induction of enzyme syntheses, (2) 

 investigate in vivo stability of adaptive enzymes of cells 

 under stresses and of availability of constituent amino acids 

 for other syntheses, (3) study specific effects of environment 

 on formation of adaptive enzymes, 

 Biol. Chem. 12^3 



Pa. Biochemical Effects of Phosphorus and Nitrogen Deficiency 



in Algae and Higher Plants . To learn (1) metabolic reactions 

 most sensitive to P and N deficiencies, (2) phosphorylation 

 mechanisms (source of ATP) in P-deficient plants and their 

 dependencies upon nutrient P, (3) phosphorylation of heptoses 

 and pentoses in plants, (h) primary effects of N deficiency 

 upon free amino acid and protein bound amino acid concentration. 

 Biol. Chem. 12& 



Pa. Oxidative Metabolism of Bacteria . (1) Learn metabolic 



reactions by which bacteria oxidize carbohydrate to completion. 



(2) Relate oxidative metabolism of bacteria to reactions by 

 which energy is trapped and synthetic C skeletons are formed. 



(3) Learn relationship between oxidative metabolism and photo- 

 metabolism in photo synthetic bacteria. 



Bact. 126^ 



Pa. Terminal Oxidases of Plants . (1) Identify and character- 



ize terminal oxidases in higher plants. (2) Study changes in 

 terminal oxidase activity as a function of tissue age. (3) 

 Estimate extent to which terminal oxidases in plant tissues 

 participate in absorption of molecular oxygen in vivo . 

 Bot., PI. Path. 1337 



Utah The Effects of Fluorides on Certain Enzymes Present in 



Selected Plant and Animal Tissues . To (1) investigate general 

 physiological basis of fluorine toxicity in plants, including 

 effects on water relations of leaves, toxicity symptoms, 

 respiration and photosynthesis, (2) learn effects of different 

 levels of soluble fluorides on esterases, phosphorylases, 

 transphosphorylases, phospho-isomerases, dehydrogenases, and 

 enzymes involved in metabolism of carbohydrates in selected 

 plant tissues of known genetic origin, (3) learn effects of 

 different levels of soluble fluorides on esterases, phospho- 

 rylases, transphosphorylases, phospho-isomerases, dehydro- 

 genases and enzymes involved in metabolism of carbohydrates 

 in selected animal products, blood, bone marrow, liver, 

 kidney, heart, and other muscles of various farm animals fed 

 under known conditions, (k) correlate possible changes in 

 enzyme systems with histo-chemical changes which occur in 

 plants and animals exposed to different levels of soluble 

 fluorides. 



Bot., Anim. Husb., Dairy Husb. U57 (W-39) 



