1907:] Experimental Treatment of Trypanosomiasis in Rats. 11 
Note upon Sodium Antimonyl Tartrate, 
By R. H. Apers Putmer, D.Sc. Lond. 
Sodium antimony] tartrate was described in 1842 by Dumas and Piria,* 
who gave it the constitution CsHs0,)Na0,Sb203H20,+ but did not state how 
they had prepared it. Clarke and Evans{ obtained a compound of the 
composition 3Na2C,H.0.¢+ 2Sb(OH)3+3H20, in 1883, by saturating tartaric 
acid with antimony trioxide and neutralising the solution with sodium 
carbonate. The first compound does not seem to have been prepared again 
since 1842. 
Sodium antimonyl tartrate was prepared according to the methods usually 
given for preparing tartar emetic, by boiling a solution of acid sodium tartrate 
(13 grammes) with a little more than the calculated quantity (10 grammes) 
of antimony ‘trioxide until the latter had almost completely passed into 
solution. On filtering and concentrating the solution to a small volume no 
crystallisation occurred, but on adding a little alcohol the whole became solid. 
This was then dissolved in about twice its volume of hot water, and alcohol 
was added until precipitation commenced, when, on cooling, the sodium 
antimony] tartrate crystallised out. This compound at the ordinary tempera- 
ture dries very slowly and has a moist appearance, but when dried i vacuo 
over sulphuric acid it becomes anhydrous and loses 24 molecules of water of 
erystallisation, resembling sodium tartrarsenite in this respect. The substance 
is very easily soluble in water and its solution reacts faintly acid to litmus. 
0°7228 gramme air-dried substance lost in vacuo over sulphuric acid 0°0920 gramme H,O 
= 12°73 per cent. 
1:0538 o 3 <5 e 0°1338 gramme H,O 
= 12°70 per cent. 
Calculated for C,H,0;NaSb.25H,O. H,O = 12°8 per cent. 
I. 0°4058 gramme substance dried tm vacuo over sulphuric acid gave 0°2332 gramme Sb,S, 
and 0°0974 gramme Na,SO,. 
Ii. 0°3780 gramme substance dried 7m vacuo over sulphuric acid gave 0°2072 gramme Sb,8, 
and 00912 gramme Na,SO,. 
Calculated for C,H,0,NaSb. Sb = 39-09 per cent. ; Na = 7°49 per cent. 
Found :—I. Sb = 39-28 Na 4578 he 
If. Sb = 39°14 ms Na = 7°81 re 
* Dumas and Piria, ‘ Liebig’s Annalen,’ 1842, vol. 44, p. 89. 
+ Old notation. 
; Clarke and Evans, ‘ Berichte,’ 1883, vol. 16, p. 2385. 
