/272 ~~ Drs. Lochhead and. Cramer. Glycogenic Changes [Jan. 1, 
is led to conclude that the placenta carries out in the earlier stages of 
pregnancy the glycogenic function for the foetus which is fulfilled later by the 
foetal liver. 
D. Glycogen of Rest of Fetal Bodies. 
Table V shows the results obtained from the analyses of the foetal bodies 
after the liver had been removed. 
Table V.—Glycogen and Weight of Remainder of Foetal Body. 
Day of gestation ...... 14. | 16. 18. 20. 21. 22. 23. 
Average weight of rest of b (058 1-90 2°74: | 3:45 | 6°50 
foetal body in grammes | | 
| Too small | ! 
Average weight of glycogen for 00018 | 0:0048 | 0:0077 | 00097 | 0:0190 
per foetus in grammes | analysis | 
Glycogen percentage ......... 5 L 0-23 | 0-25 |028 | 0-28 0-29 
Day of gestation ...... 24. 25, 26. oe 28) eae) 
Average weight of rest of | 8°75 18 ‘20 10 ‘50 30°17 30°00 | 24°56 
foetal body in grammes 
Average weight of glycogen| 0°0320 | 0:°0692 , 0:°0241 0 1026 0 ‘1314 | 0 -0663 
per fetus in grammes 
Glycogen percentage ......... 0°37 0°37 0°23 0°34 0°44 | 0:27 
The great increase in the total amount of glycogen per foetus is, of course, 
to be expected along with the great increase in weight as pregnancy advances. 
The percentage amount is also higher in the last week of pregnancy than in 
the period immediately preceding, but the variation is only slight. The 
results agree with the work of other investigators in showing that embryonic 
tissues are not particularly rich in glycogen. , 
elation of Fetal Growth to Glycogen Percentage—Fig. 2 represents 
graphically the increase in fcetal weight and the increase in the percentage 
of the total foetal glycogen from the 18th day to the end of gestation, as 
calculated from Tables IV and V. As is to be expected, the curve of the 
foetal growth rises as pregnancy advances. Corresponding to this we have a 
general rise, not only in the total amount of glycogen, but also in the glycogen 
percentage of the foetus. In the two exceptional cases where the fcetal 
weight was lower than that of the preceding day there was also a decrease, 
not only in the absolute amount of glycogen, but also in the percentage ; 
¢., the glycogen was decreased out of proportion. 
