1908.] The Life-history of Trypanosoma equiperdum. 
nuclear centrosome to the nucleus 
instead of a continuous band. 
As a matter of fact, the difference 
is really less than this, for in 
T. equiperdum the extra-nuclear 
centrosome not only seems to be 
connected with the detached 
portion, but also several portions 
may be detached, one after 
another. (Compare Diagrams I 
and IT, a, 0, ¢.) 
The phase wherein the detach- 
ment of a portion of the extra- 
nuclear centrosome which passes 
to the nucleus takes place is of 
very short duration, and at the 
same time appears to affect the 
great majority of the parasites 
present in the blood, just in the 
same way that an epidemic of 
conjugation among infusoria will 
affect at the same time a whole 
colony. In the specimens from 
which the figures aregiven the pro- 
cess was in full swing at 10 AM., 
but by 5 P.M. had come to an end. 
At the time this process is 
going forward, and immediately 
afterwards, still further changes 
take place, corresponding to the 
changes which in 7. gambvense 
precede the production of the 
latent bodies. But the latent 
bodies of dourine are very much 
larger than those in 7’. gambiense, 
and consequently their formation 
is proportionately less difficult to 
elucidate. 
When the process of translocation of a portion of the extra-nuclear 
centrosome has come to an end, and the parasites have again passed through 
2A 
VOL. LXXX.—B. 
Diagram II.—Showing the cyclical metamorphosis occurring in Trypanosoma equiperdum in the blood of an infected rat. 
a. The 
b’. 
c. The formation 
The 
b. The interaction between the extra-nuclear centrosome and the nucleus. 
longitudinal fission which occurs after the interaction between the extra-nuclear centrosome and the nucleus. 
of the latent bodies and the growth of their flagelle. 
longitudinal fission of the parasites. 
295 
